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Description
  • LDL aferéza je velmi účinnou metodou léčby hypercholesterolémie rezistentní na jiné formy léčby. Abychom dosáhli nejlepšího možného využití adsorbérů, modelovali jsme průběh procedury pomocí počítačového programu. Cílem této studie bylo ověřit jeho předpovědi v reálném klinickém provozu. Výsledky prokazují velmi dobrou shodu mezi předpovězenými a reálnými hodnotami ve většině procedur, v některých případech jsme však pozorovali nevelké odchylky (řádu 0,05 mmol/l), které byly zapříčiněny úpravami režimu procedury, nutnými z technických důvodů. (cs)
  • LDL-apheresis is a very effective method in the treatment of resistant hypercholesterolemia when other therapy fails. To maximize the efficacy of the use of LDL-absorbers we created a computerized model. The aim of this study is to verify it in a real clinical use. The results show a very good match between calculated levels and the real laboratory results in most procedures, but in some procedures we observed minor differences (0.05 mmol/L), which was caused by procedure adjustments due to technical reasons.
  • LDL-apheresis is a very effective method in the treatment of resistant hypercholesterolemia when other therapy fails. To maximize the efficacy of the use of LDL-absorbers we created a computerized model. The aim of this study is to verify it in a real clinical use. The results show a very good match between calculated levels and the real laboratory results in most procedures, but in some procedures we observed minor differences (0.05 mmol/L), which was caused by procedure adjustments due to technical reasons. (en)
Title
  • Optimization of therapeutic procedure during LDL-apheresis - verification of the computerized model in clinical practise
  • Optimization of therapeutic procedure during LDL-apheresis - verification of the computerized model in clinical practise (en)
  • Optimalizace terapeutických LDL-aferéz: ověření počítačem podporovaného modelu (cs)
skos:prefLabel
  • Optimization of therapeutic procedure during LDL-apheresis - verification of the computerized model in clinical practise
  • Optimization of therapeutic procedure during LDL-apheresis - verification of the computerized model in clinical practise (en)
  • Optimalizace terapeutických LDL-aferéz: ověření počítačem podporovaného modelu (cs)
skos:notation
  • RIV/00216208:11150/07:00003667!RIV08-MZ0-11150___
http://linked.open.../vavai/riv/strany
  • 39;45
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR8505)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 439910
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/07:00003667
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • LDL apheresis; familial hypercholesterolemia; atherosclerosis; immunoadsorption (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [E99FEDDCB4D6]
http://linked.open...i/riv/nazevZdroje
  • Transfusion and Apheresis Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 36
http://linked.open...iv/tvurceVysledku
  • Bláha, Milan
  • Stránský, Pravoslav
  • Bláha, Vladimír
  • Mašín, Vladimír
issn
  • 1473-0502
number of pages
http://localhost/t...ganizacniJednotka
  • 11150
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