About: Urinary Neopterin and Microalbumiuria in Patients Treated by Low-density Lipoprotein Apheresis     Goto   Sponge   NotDistinct   Permalink

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Description
  • V této studii jsme u 10 pacientů s těžkou primární lipoproteinovou chorobou zkoumali po jedné LDL-aferéze močový neopterin, což je specifický marker aktivace makrofágů a mikroalbuminurie, která indikuje generalizovanou vaskulární dysfunkci. Korelace mezi mikroalbuminurií, neopterinem a preaferetickými koncentracemi cholesterolu naznačují možné spojení mezi mikrovaskulární dysfunkcí, aktivitou makrofágů a stupněm hyperlipidémie. Tyto výsledky je však třeba interpretovat opatrně díky malé skupině vyšetřovaných pacientů. (cs)
  • In the present study, we have investigated urinary neopterin, a specific marker of macrophage activation and microalbuminuria, an indicator of generalized vascular dysfunction, after a single LDL-apheresis procedure in 10 patients with severe primary lipoprotein disorder. the correlations between microalbuminuria, neopterin and pre-apheretic cholesterol concentrations indicate a possible connection between microvascular dysfunction, macrophage activity and severity of hyperlipidemia, but these results should be interpreted with caution because of small number of subjects evaluated.
  • In the present study, we have investigated urinary neopterin, a specific marker of macrophage activation and microalbuminuria, an indicator of generalized vascular dysfunction, after a single LDL-apheresis procedure in 10 patients with severe primary lipoprotein disorder. the correlations between microalbuminuria, neopterin and pre-apheretic cholesterol concentrations indicate a possible connection between microvascular dysfunction, macrophage activity and severity of hyperlipidemia, but these results should be interpreted with caution because of small number of subjects evaluated. (en)
Title
  • Urinary Neopterin and Microalbumiuria in Patients Treated by Low-density Lipoprotein Apheresis
  • Neopterin v moči a mikroalbuminurie u pacientů léčených LDL aferézou (cs)
  • Urinary Neopterin and Microalbumiuria in Patients Treated by Low-density Lipoprotein Apheresis (en)
skos:prefLabel
  • Urinary Neopterin and Microalbumiuria in Patients Treated by Low-density Lipoprotein Apheresis
  • Neopterin v moči a mikroalbuminurie u pacientů léčených LDL aferézou (cs)
  • Urinary Neopterin and Microalbumiuria in Patients Treated by Low-density Lipoprotein Apheresis (en)
skos:notation
  • RIV/00216208:11150/05:00004726!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany
  • 174;183
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
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  • 548021
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/05:00004726
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  • Urinary; Neopterin; Microalbumiuria; Patients; Treated; Low-density; Lipoprotein; Apheresis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [543696D6AEA7]
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  • Pteridines
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http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 16
http://linked.open...iv/tvurceVysledku
  • Blažek, Martin
  • Bláha, Milan
  • Melichar, Bohuslav
  • Solichová, Dagmar
  • Zadák, Zdeněk
  • Bláha, Vladimír
  • Mašín, Vladimír
issn
  • 0933-4807
number of pages
http://localhost/t...ganizacniJednotka
  • 11150
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