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| rdf:type
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| Description
| - Cílem práce bylo popsat histologické změny periferních nervů po jejich uvolnění a uložení do různých tkání. Operovali jsme 18 krys (samci) rozdělených do 3 skupin. V první jsme uvolnili n. femoralis vpravo, ve druhé byl nerv obalen podkožním tukem, ve třetí byl uložen do příčně pruhovaného svalu. Zvířata byla utracena po 6 týdnech exsanquinací. V první skupině n. femoralis nevykázal žádné patologické změny, ve druhé skupině byl nález u 3 zvířat normální nebo skoro normální a u 3 z nich jsme nalezli perineurální fibrózu a degeneraci axonu. Histologické vyšetření ve třetí skupině prokázalo poškození axonu. Experimenty napodobují situaci u nemocných a získané výsledky pomohou v rozhodování o léčbě poranění periferních nervů. (cs)
- The aim of our study was to describe histopathology of the peripheral nerve after its circular release followed by embedding in different environs. We operated on 18 male rats divided into 3 groups. In the first group right femoral nerve was surgically released. In the second group the nerve was enveloped by the subcutaneous fat flap. In the third one the nerve was wrapped up by the skeletal muscle. Six weeks later the animals wire killed by exsanguination. The femoral nerve, in the first group, did not show any pathological changes. In the second group 3 animals appeared normal or nerarly normal, nevertheless in 3 of them perineural fibrosis and axonal degeneration were observed. Histological reaction in the third group disclosed dispersed axonal injury. Our experiments using rat model imitate situation in humans. The results obtained will help us in making meaningful decision when performing peripheral nerve injury.
- The aim of our study was to describe histopathology of the peripheral nerve after its circular release followed by embedding in different environs. We operated on 18 male rats divided into 3 groups. In the first group right femoral nerve was surgically released. In the second group the nerve was enveloped by the subcutaneous fat flap. In the third one the nerve was wrapped up by the skeletal muscle. Six weeks later the animals wire killed by exsanguination. The femoral nerve, in the first group, did not show any pathological changes. In the second group 3 animals appeared normal or nerarly normal, nevertheless in 3 of them perineural fibrosis and axonal degeneration were observed. Histological reaction in the third group disclosed dispersed axonal injury. Our experiments using rat model imitate situation in humans. The results obtained will help us in making meaningful decision when performing peripheral nerve injury. (en)
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| Title
| - The changes of peripheral nerve microsutructure after surgical manipulation - experiment on rat model
- The changes of peripheral nerve microsutructure after surgical manipulation - experiment on rat model (en)
- Změny v mikrostruktuře periferního nervu po chirurgické manipulaci - experiment na kryse (cs)
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| skos:prefLabel
| - The changes of peripheral nerve microsutructure after surgical manipulation - experiment on rat model
- The changes of peripheral nerve microsutructure after surgical manipulation - experiment on rat model (en)
- Změny v mikrostruktuře periferního nervu po chirurgické manipulaci - experiment na kryse (cs)
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| skos:notation
| - RIV/00216208:11150/05:00003602!RIV06-MSM-11150___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(IAA148404), P(NR8404), Z(MSM0021620820)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/05:00003602
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Nerve microstructure; perineural fibrosis; axonal damage; animals models; nerve histology (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Acta Medica (Hradec Králové)
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Cerman, Jaroslav
- Ehler, Edvard
- Němeček, Stanislav
- Kanta, Martin
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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