About: Long term and repeated electron Microscopy and PCR detection of Borrelia burgdorfery sensu lato after an antibiotic treatment     Goto   Sponge   NotDistinct   Permalink

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Description
  • The diagnosis of Lyme disease in 18 patients has been proved by detection of Borrelia burgdorferi sensu lato when using immunoelectron microscopy or detecting its nucleic acid by PCR in the plasma or the cerebrospinal fluid. The positive results occurred in the plasma or in the cerebrospinal fluid in the period of 4-68 months after an antibiotic treatment. The typical clinical manifestations of Lyme disease were observed in 9 patients and non-specific symptoms in another 9 patients. According to presented results we can recommend repeated examination using PCR of the plasma and other biological specimens in the individuals with persistent or recurring complaints after an acute form of Lyme disease and its antibiotic treatment. Also examination of the cerebrospinal fluid with non-specific symptoms and simultaneously displayed pathology electroencephalogram and/or magnetic resonance imaging findings can be advantageous.
  • The diagnosis of Lyme disease in 18 patients has been proved by detection of Borrelia burgdorferi sensu lato when using immunoelectron microscopy or detecting its nucleic acid by PCR in the plasma or the cerebrospinal fluid. The positive results occurred in the plasma or in the cerebrospinal fluid in the period of 4-68 months after an antibiotic treatment. The typical clinical manifestations of Lyme disease were observed in 9 patients and non-specific symptoms in another 9 patients. According to presented results we can recommend repeated examination using PCR of the plasma and other biological specimens in the individuals with persistent or recurring complaints after an acute form of Lyme disease and its antibiotic treatment. Also examination of the cerebrospinal fluid with non-specific symptoms and simultaneously displayed pathology electroencephalogram and/or magnetic resonance imaging findings can be advantageous. (en)
  • Diagnóza Lymeské boreliózy byla u 18 pacientů potvrzena detekcí Borrelia burgdorferi sensu lato pomocí imunoelektronové mikroskopie nebo průkazem nukleových kyselin borelií v plazmě či mozkomíšním moku pomocí PCR. Pozitivní výsledky se objevily v období 4-68 měsíců po antibiotické léčbě. Typické klinické projevy Lymeské boreliózy byly pozorovány u 9 pacientů a nespecifické projevy u dalších 9 pacientů. Podle předkládaných výsledků můžeme doporučit opakované vyšetřování plazmya dalších biologických vzorků pomocí PCR u pacientů s přetrvávajícími nebo znovu se objevujícími potížemi po prodělání akutní formy Lymeské boreliózy léčené antibiotiky. Také vyšetřování mozkomíšního moku u pacientů s nespecifickými příznaky a současnými patologickými nálezy na elektroencefalogramu a/nebo magnetické rezonanci může být výhodné. (cs)
Title
  • Dlouhodobá a opakovaná elektronmikroskopická a PCR detekce Borrelia burgdorfery sensulato po terapii antibiotiky (cs)
  • Long term and repeated electron Microscopy and PCR detection of Borrelia burgdorfery sensu lato after an antibiotic treatment
  • Long term and repeated electron Microscopy and PCR detection of Borrelia burgdorfery sensu lato after an antibiotic treatment (en)
skos:prefLabel
  • Dlouhodobá a opakovaná elektronmikroskopická a PCR detekce Borrelia burgdorfery sensulato po terapii antibiotiky (cs)
  • Long term and repeated electron Microscopy and PCR detection of Borrelia burgdorfery sensu lato after an antibiotic treatment
  • Long term and repeated electron Microscopy and PCR detection of Borrelia burgdorfery sensu lato after an antibiotic treatment (en)
skos:notation
  • RIV/00216208:11150/04:00004653!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany
  • 6;11
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  • 571780
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  • RIV/00216208:11150/04:00004653
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  • repeated; electron; Microscopy; detection; Borrelia; burgdorfery; sensu; after; antibiotic; treatment (en)
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  • CZ - Česká republika
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  • [AFD9CB9A125B]
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  • Central European Journal of Public Health
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  • 12
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  • Dostál, Václav
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  • 1210-7778
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