About: Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer     Goto   Sponge   NotDistinct   Permalink

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Description
  • Immunoglobulin A (IgA) pemphigus is a clinically distinct variant of penphigus characterized by intercellular IgA deposition in the epidermis. Recently, an IgA/Immunoglobulin G (IgG) subset of penphigus with IgA and IgG anti-keratinocyte cell surface antibodies has been described. Both IgA and IgA(IgG penphigus have been associated with internal malignancies. Above all, monoclonal IgA gammopathy in patients with IgA penphigus has been reported, and lung cancers in association with IgA/IgG pemphigus have been described. IgA pepnpihus can be successfully treated with dapsone, whereas therapeutic management of IgG/igA pemphigus is not well established yet. We report a rare case of a patient, who developed atypical pemphigus with both IgA and IgG autoantibodies and an underlying lung cancer, successfully treated with corticosteroids and dapsone.
  • Immunoglobulin A (IgA) pemphigus is a clinically distinct variant of penphigus characterized by intercellular IgA deposition in the epidermis. Recently, an IgA/Immunoglobulin G (IgG) subset of penphigus with IgA and IgG anti-keratinocyte cell surface antibodies has been described. Both IgA and IgA(IgG penphigus have been associated with internal malignancies. Above all, monoclonal IgA gammopathy in patients with IgA penphigus has been reported, and lung cancers in association with IgA/IgG pemphigus have been described. IgA pepnpihus can be successfully treated with dapsone, whereas therapeutic management of IgG/igA pemphigus is not well established yet. We report a rare case of a patient, who developed atypical pemphigus with both IgA and IgG autoantibodies and an underlying lung cancer, successfully treated with corticosteroids and dapsone. (en)
Title
  • Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer
  • Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer (en)
skos:prefLabel
  • Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer
  • Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer (en)
skos:notation
  • RIV/00216208:11140/14:10210629!RIV15-MSM-11140___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 4
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http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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  • 27076
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11140/14:10210629
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • lung cancer; IgA/IgG pemphigus; dapsone (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [F79B54DB8744]
http://linked.open...i/riv/nazevZdroje
  • Dermatologic Therapy
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 27
http://linked.open...iv/tvurceVysledku
  • Cetkovská, Petra
  • Komorousová, Michaela
  • Lomicová, Iva
http://linked.open...ain/vavai/riv/wos
  • 000340279600012
issn
  • 1396-0296
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/dth.12126
http://localhost/t...ganizacniJednotka
  • 11140
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