About: Pediatric Case of Primary Cutaneous Eosinophil-Rich CD30 Anaplastic Large-Cell Lymphoma With Follicular Mucinosis

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We report a pediatric case of primary cutaneous CD30 anaplastic large-cell lymphoma showing a combination of rare histopathologic features. The patient was a 14-year-old boy who had a solitary 2 x 1-cm ulcerated nodule with purulent discharge and undermined borders located in the right preauricular area that had been present for 3 weeks. Histopathologically, there was a dense, nonepidermotropic multinodular to diffuse infiltrate involving the reticular dermis and, focally, the subcutis. The infiltrate was composed of numerous eosinophils, neutrophils, small well-differentiated lymphocytes, and large pleomorphic and anaplastic cells. Eosinophils dominated the infiltrate. Focally, the infiltrate was accentuated around hair follicles, many of which manifested features of follicular mucinosis and/or collections of neutrophils in the follicular epithelium. Occasional hair follicles were partly destroyed by the infiltrate. A conspicuous feature was a prominent myxoid change in the stroma surrounding the hair follicles and eccrine glands. Immunohistochemically, the large lymphoid cells expressed CD2, CD3, CD4, and CD30. We report a pediatric case of primary cutaneous CD30 anaplastic large-cell lymphoma showing a combination of rare histopathologic features. The patient was a 14-year-old boy who had a solitary 2 x 1-cm ulcerated nodule with purulent discharge and undermined borders located in the right preauricular area that had been present for 3 weeks. Histopathologically, there was a dense, nonepidermotropic multinodular to diffuse infiltrate involving the reticular dermis and, focally, the subcutis. The infiltrate was composed of numerous eosinophils, neutrophils, small well-differentiated lymphocytes, and large pleomorphic and anaplastic cells. Eosinophils dominated the infiltrate. Focally, the infiltrate was accentuated around hair follicles, many of which manifested features of follicular mucinosis and/or collections of neutrophils in the follicular epithelium. Occasional hair follicles were partly destroyed by the infiltrate. A conspicuous feature was a prominent myxoid change in the stroma surrounding the hair follicles and eccrine glands. Immunohistochemically, the large lymphoid cells expressed CD2, CD3, CD4, and CD30. (en)
Title	Pediatric Case of Primary Cutaneous Eosinophil-Rich CD30 Anaplastic Large-Cell Lymphoma With Follicular Mucinosis Pediatric Case of Primary Cutaneous Eosinophil-Rich CD30 Anaplastic Large-Cell Lymphoma With Follicular Mucinosis (en)
skos:prefLabel	Pediatric Case of Primary Cutaneous Eosinophil-Rich CD30 Anaplastic Large-Cell Lymphoma With Follicular Mucinosis Pediatric Case of Primary Cutaneous Eosinophil-Rich CD30 Anaplastic Large-Cell Lymphoma With Follicular Mucinosis (en)
skos:notation	RIV/00216208:11140/14:10210520!RIV15-MSM-11140___
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kazakov, Dmitry Kacerovská, Denisa Michal, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Plzni
http://linked.open...dnocenehoVysledku	36039
http://linked.open...ai/riv/idVysledku	RIV/00216208:11140/14:10210520
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pediatric case; lymphomatoid papulosis; primary cutaneous CD30+ anaplastic large-cell lymphoma; CD30-positive lymphoproliferative disorders (en)
http://linked.open.../riv/klicoveSlovo	CD30-positive lymphoproliferative disorders pediatric case primary cutaneous CD30+ anaplastic large-cell lymphoma lymphomatoid papulosis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[AE2201DCADAC]
http://linked.open...i/riv/nazevZdroje	American Journal of Dermatopathology
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	36
http://linked.open...iv/tvurceVysledku	Kacerovská, Denisa Kazakov, Dmitry Michal, Michal
http://linked.open...ain/vavai/riv/wos	000337303600004
issn	0193-1091
number of pages	3 (xsd:int)
http://bibframe.org/vocab/doi	10.1097/DAD.0b013e3182914c89
http://localhost/t...ganizacniJednotka	11140

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