About: Histology of ventral abdominal incisions in a porcine model - in vivo experiment with incorporation of artificial meshes

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About: Histology of ventral abdominal incisions in a porcine model - in vivo experiment with incorporation of artificial meshes Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We examined the tissue reaction to incorporation of two types of artificial tissue-engineered meshes in porcine abdominal wall after 6 and 12 weeks of regeneration. Using six quantitative histological parameters, the area fraction of type I collagen, actin-positive smooth muscle cells and myofibroblasts, and the microvessel density was assessed in the healing incision and 2 cm laterally from the incision. From histological point of view, both types of scaffolds were well and uniformly integrated within the collagenous connective tissue of the healing incision. The presence of both types of scaffolds led to increased amount of contractile myofibroblasts within the healing incision, but the amount of microvessels in samples with scaffolds was comparable with samples without scaffolds. In one of these scaffolds, the microvessel density was positively correlated with the fraction of type I collagen. We examined the tissue reaction to incorporation of two types of artificial tissue-engineered meshes in porcine abdominal wall after 6 and 12 weeks of regeneration. Using six quantitative histological parameters, the area fraction of type I collagen, actin-positive smooth muscle cells and myofibroblasts, and the microvessel density was assessed in the healing incision and 2 cm laterally from the incision. From histological point of view, both types of scaffolds were well and uniformly integrated within the collagenous connective tissue of the healing incision. The presence of both types of scaffolds led to increased amount of contractile myofibroblasts within the healing incision, but the amount of microvessels in samples with scaffolds was comparable with samples without scaffolds. In one of these scaffolds, the microvessel density was positively correlated with the fraction of type I collagen. (en)
Title	Histology of ventral abdominal incisions in a porcine model - in vivo experiment with incorporation of artificial meshes Histology of ventral abdominal incisions in a porcine model - in vivo experiment with incorporation of artificial meshes (en)
skos:prefLabel	Histology of ventral abdominal incisions in a porcine model - in vivo experiment with incorporation of artificial meshes Histology of ventral abdominal incisions in a porcine model - in vivo experiment with incorporation of artificial meshes (en)
skos:notation	RIV/00216208:11140/12:10191822!RIV14-MSM-11140___
http://linked.open...avai/riv/aktivita	N
http://linked.open...avai/riv/aktivity	N
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Tonar, Zbyněk Králíčková, Milena
http://linked.open.../riv/druhVysledku	V/S - Souhrnná výzkumná zpráva
http://linked.open...iv/duvernostUdaju	C - Předmět podléhá obchodnímu tajemství (§17 až 20 Obchodního zákoníku), ale některé údaje jsou upraveny tak, aby byly zveřejnitelné
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Plzni
http://linked.open...dnocenehoVysledku	139073
http://linked.open...ai/riv/idVysledku	RIV/00216208:11140/12:10191822
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	quantitative histology; wound healing; scaffold; mesh; incisional hernia repair (en)
http://linked.open.../riv/klicoveSlovo	mesh wound healing scaffold incisional hernia repair quantitative histology
http://linked.open...ontrolniKodProRIV	[19DEAD8F805C]
http://linked.open...telVyzkumneZpravy	CB Bio s.r.o.
http://linked.open...in/vavai/riv/obor	EA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Tonar, Zbyněk Králíčková, Milena
http://linked.open...rzeVyzkumneZpravy	Neuveden
number of pages	19 (xsd:int)
http://localhost/t...ganizacniJednotka	11140

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