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Description
  • Accumulating data indicate that AKI can trigger several immune, metabolic and humoral pathways, thus potentially contributing to distant organ dysfunction and overall morbidity and mortality. Better insights into bidirectional and synergistic pathways linking sepsis and AKI might open the window for new therapeutic approaches that interrupt this vicious circle. In this review, we discuss the rationale for and current understanding of the bidirectional relationship between AKI and sepsis.
  • Accumulating data indicate that AKI can trigger several immune, metabolic and humoral pathways, thus potentially contributing to distant organ dysfunction and overall morbidity and mortality. Better insights into bidirectional and synergistic pathways linking sepsis and AKI might open the window for new therapeutic approaches that interrupt this vicious circle. In this review, we discuss the rationale for and current understanding of the bidirectional relationship between AKI and sepsis. (en)
Title
  • Sepsis and acute kidney injure are bidirectional
  • Sepsis and acute kidney injure are bidirectional (en)
skos:prefLabel
  • Sepsis and acute kidney injure are bidirectional
  • Sepsis and acute kidney injure are bidirectional (en)
skos:notation
  • RIV/00216208:11140/11:10103105!RIV12-MSM-11140___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021620819)
http://linked.open...iv/cisloPeriodika
  • září
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 228918
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11140/11:10103105
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • inflammation; remote injury; organ dysfunction; sepsis; acute kidney injury (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV
  • [84E702625DC9]
http://linked.open...i/riv/nazevZdroje
  • Contributions to Nephrology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 174
http://linked.open...iv/tvurceVysledku
  • Chvojka, Jiří
  • Kroužecký, Aleš
  • Matějovič, Martin
  • Novák, Ivan
  • Raděj, Jaroslav
  • Karvunidis, Thomas
  • Ledvinová, Lenka
http://linked.open...n/vavai/riv/zamer
issn
  • 0302-5144
number of pages
http://bibframe.org/vocab/doi
  • 10.1159/000329239
http://localhost/t...ganizacniJednotka
  • 11140
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