About: ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia     Goto   Sponge   NotDistinct   Permalink

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Description
  • Childhood acute lymphoblastic leukemia (ALL) demonstrates clinical and biological heterogeneity, which is largely sustained by a diverse genetic background. Today, the majority of children with ALL treated on modern treatment protocols can expect to achieve long-term cure, but still a significant proportion of patients suffer therapy-related toxicity and disease relapse. Thus, identification of new prognostic markers to improve initial risk assessment for subsequent treatment tailoring remains an important goal in ALL research.
  • Childhood acute lymphoblastic leukemia (ALL) demonstrates clinical and biological heterogeneity, which is largely sustained by a diverse genetic background. Today, the majority of children with ALL treated on modern treatment protocols can expect to achieve long-term cure, but still a significant proportion of patients suffer therapy-related toxicity and disease relapse. Thus, identification of new prognostic markers to improve initial risk assessment for subsequent treatment tailoring remains an important goal in ALL research. (en)
Title
  • ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia
  • ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia (en)
skos:prefLabel
  • ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia
  • ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia (en)
skos:notation
  • RIV/00216208:11130/14:10292809!RIV15-MSM-11130___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
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  • 14925
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  • RIV/00216208:11130/14:10292809
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  • subtype; bfm 2000 protocol (en)
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  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [2AF0BFE3BF07]
http://linked.open...i/riv/nazevZdroje
  • Leukemia
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...v/svazekPeriodika
  • 28
http://linked.open...iv/tvurceVysledku
  • Eckert, C.
  • Zimmermann, M.
  • Zuna, Jan
  • Stuchlý, Jan
  • Cario, G.
  • Teigler-Schlegel, A.
  • Schrappe, M.
  • Meissner, B.
  • Stanulla, M.
  • Zimmermannová, Olga
  • Bartram, C. R.
  • Doerge, P.
  • Karawajew, L.
  • Koehler, R.
  • Kubričanová Žaliová, Markéta
  • Moericke, A.
  • Rhein, P.
http://linked.open...ain/vavai/riv/wos
  • 000329441200020
issn
  • 0887-6924
number of pages
http://bibframe.org/vocab/doi
  • 10.1038/leu.2013.282
http://localhost/t...ganizacniJednotka
  • 11130
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