About: Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.3109/00016489.2013.840924
Description	Conclusion: Our results encourage the notion that the pharynx could be an extragastric reservoir of Helicobacter pylori (HP). The study confirmed the presence of HP in adenotonsillar tissue in children. It could have importance in the pathophysiology of upper respiratory diseases. However, its precise role in these processes remains unclear and requires further studies. Objective: A prospective study was carried out to evaluate the presence of HP in tonsillar and adenoid tissue in children. The study focused on real-time PCR analyzing CagA and VacA genotypes of HP strains. Methods: A total of 37 consecutive pediatric patients with adenotonsillar hypertrophy indicated for surgery were observed in a prospective study. Adenoidectomy and/or tonsillectomy was performed in each patient; 49 specimens were taken, 32 from adenoids and 17 from tonsils. The presence of HP and its genotype were tested in all samples by real-time PCR analysis. Results: Of 49 samples analyzed, 48 were positive for the presence of HP (98%), so only 1 sample was negative. While the genotype VacAs1bm2 was definitely dominant in adenoid tissue, wider distribution was observed in tonsillar tissue. Cag(+) strains represented one-fifth of all samples (21%). Conclusion: Our results encourage the notion that the pharynx could be an extragastric reservoir of Helicobacter pylori (HP). The study confirmed the presence of HP in adenotonsillar tissue in children. It could have importance in the pathophysiology of upper respiratory diseases. However, its precise role in these processes remains unclear and requires further studies. Objective: A prospective study was carried out to evaluate the presence of HP in tonsillar and adenoid tissue in children. The study focused on real-time PCR analyzing CagA and VacA genotypes of HP strains. Methods: A total of 37 consecutive pediatric patients with adenotonsillar hypertrophy indicated for surgery were observed in a prospective study. Adenoidectomy and/or tonsillectomy was performed in each patient; 49 specimens were taken, 32 from adenoids and 17 from tonsils. The presence of HP and its genotype were tested in all samples by real-time PCR analysis. Results: Of 49 samples analyzed, 48 were positive for the presence of HP (98%), so only 1 sample was negative. While the genotype VacAs1bm2 was definitely dominant in adenoid tissue, wider distribution was observed in tonsillar tissue. Cag(+) strains represented one-fifth of all samples (21%). (en)
Title	Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children (en)
skos:prefLabel	Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children (en)
skos:notation	RIV/00216208:11130/14:10195535!RIV15-MSM-11130___
http://linked.open...avai/riv/aktivita	I P V
http://linked.open...avai/riv/aktivity	I, P(NT11523), V
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Katra, Rami
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	39174
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/14:10195535
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pharynx; PCR; tonsils; Adenoid (en)
http://linked.open.../riv/klicoveSlovo	PCR pharynx tonsils Adenoid
http://linked.open...odStatuVydavatele	NO - Norské království
http://linked.open...ontrolniKodProRIV	[648496F75DBD]
http://linked.open...i/riv/nazevZdroje	Acta Oto-Laryngologica
http://linked.open...in/vavai/riv/obor	FF
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Correlation of Helicobacter pylori and gastroesophageal rephlux to etiopathogenesis of oropharyngeal and laryngeal tumors
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	134
http://linked.open...iv/tvurceVysledku	Astl, Jaromír Katra, Rami Pavlík, Emil Šterzl, Ivan Nártová, Eva Kraus, Jaroslav
http://linked.open...ain/vavai/riv/wos	000329058700013
issn	0001-6489
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.3109/00016489.2013.840924
http://localhost/t...ganizacniJednotka	11130

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