About: Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.3390/ijms140713391
Description	Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution. Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution. (en)
Title	Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery (en)
skos:prefLabel	Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery (en)
skos:notation	RIV/00216208:11130/13:10190865!RIV14-GA0-11130___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED1.1.00/02.0068), P(GAP301/10/0356)
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Eckschlager, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	61645
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/13:10190865
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nanoparticles; doxorubicin; magnetic particles; nanomedicine; cancer (en)
http://linked.open.../riv/klicoveSlovo	cancer nanoparticles doxorubicin magnetic particles nanomedicine
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[ADA156D77E0C]
http://linked.open...i/riv/nazevZdroje	International Journal of Molecular Sciences
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology Study of contribution of different DNA-damaging mechanisms to toxicity of cytostatics to human chemosensitive and chemoresistant neuroblastomas
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	14
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Eckschlager, Tomáš Kizek, René Stiborová, Marie Vaculovičová, Markéta Dostálová, Simona Blažková, Iva Kopel, Pavel Nguyen, Hoai Viet Stanisavljević, Maja
http://linked.open...ain/vavai/riv/wos	000322171700029
issn	1422-0067
number of pages	12 (xsd:int)
http://bibframe.org/vocab/doi	10.3390/ijms140713391
http://localhost/t...ganizacniJednotka	11130

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