About: Lung Mast Cells and Hypoxic Pulmonary Hypertension     Goto   Sponge   NotDistinct   Permalink

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Description
  • Hypoxic pulmonary hypertension (HPH) is a syndrome characterized by the increase of pulmonary vascular tone and the structural remodeling of peripheral pulmonary arteries. Mast cells have an important role in many inflammatory diseases and they are also involved in tissue remodeling. Tissue hypoxia is associated with mast cell activation and the release of proteolytic enzymes, angiogenic and growth factors which mediate tissue destruction and remodeling in a variety of physiological and pathological conditions. Here we focused on the role of mast cells in the pathogenesis of hypoxic pulmonary hypertension from the past to the present.
  • Hypoxic pulmonary hypertension (HPH) is a syndrome characterized by the increase of pulmonary vascular tone and the structural remodeling of peripheral pulmonary arteries. Mast cells have an important role in many inflammatory diseases and they are also involved in tissue remodeling. Tissue hypoxia is associated with mast cell activation and the release of proteolytic enzymes, angiogenic and growth factors which mediate tissue destruction and remodeling in a variety of physiological and pathological conditions. Here we focused on the role of mast cells in the pathogenesis of hypoxic pulmonary hypertension from the past to the present. (en)
Title
  • Lung Mast Cells and Hypoxic Pulmonary Hypertension
  • Lung Mast Cells and Hypoxic Pulmonary Hypertension (en)
skos:prefLabel
  • Lung Mast Cells and Hypoxic Pulmonary Hypertension
  • Lung Mast Cells and Hypoxic Pulmonary Hypertension (en)
skos:notation
  • RIV/00216208:11130/12:8077!RIV13-MSM-11130___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0510), P(GA305/08/0108)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 147600
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11130/12:8077
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Pulmonary hypertension; Mast cells; Hypoxia; Tissue remodeling; vascular smooth-muscle; serine elastase inhibitor; timp-1 gene-transfer; matrix metalloproteinases; disodium-cromoglycate; cromolyn sodium; nitric-oxide; in-vitro; rats; vasoconstriction (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [24B3994ED08E]
http://linked.open...i/riv/nazevZdroje
  • Physiological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 61
http://linked.open...iv/tvurceVysledku
  • Maxová, Hana
  • Vízek, Martin
  • Herget, Jan
http://linked.open...ain/vavai/riv/wos
  • 000302195300001
issn
  • 0862-8408
number of pages
http://localhost/t...ganizacniJednotka
  • 11130
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