About: Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth     Goto   Sponge   NotDistinct   Permalink

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Description
  • Shb (an adapter protein)functions in the VEGF signalization. The present study was performed to address endothelial function in the Shb knockout mouse and its relevance for tumor angiogenesis. Tumor growth was retarded in Shb mutated mice and this was correlated with decreased tumor angiogenesis. It is concluded that Shb plays an important role in mouse angiogenesis and Shb signaling may provide novel means to regulate tumor angiogenesis.
  • Shb (an adapter protein)functions in the VEGF signalization. The present study was performed to address endothelial function in the Shb knockout mouse and its relevance for tumor angiogenesis. Tumor growth was retarded in Shb mutated mice and this was correlated with decreased tumor angiogenesis. It is concluded that Shb plays an important role in mouse angiogenesis and Shb signaling may provide novel means to regulate tumor angiogenesis. (en)
Title
  • Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
  • Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth (en)
skos:prefLabel
  • Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
  • Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth (en)
skos:notation
  • RIV/00216208:11130/09:5568!RIV10-MSM-11130___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021620808)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 311745
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11130/09:5568
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Shb; knockout mouse; tumor angiogenesis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [0C6093FA94BE]
http://linked.open...i/riv/nazevZdroje
  • Cancer Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 69
http://linked.open...iv/tvurceVysledku
  • Kříž, Vítězslav
  • Mareš, Jaroslav
  • Welsh, Michael
  • Čalounová, Gabriela
  • Funa, Nina
  • Akerblom, Bjorn
  • Betsholtz, Christer
  • Larsson, Erik
  • Sun, Ying
  • Zang, Guangxiang
http://linked.open...ain/vavai/riv/wos
  • 000263937800058
http://linked.open...n/vavai/riv/zamer
issn
  • 0008-5472
number of pages
http://localhost/t...ganizacniJednotka
  • 11130
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