About: Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study

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About: Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A standardized, sensitive and universal method for minimal residual disease (MRD) detection in acute myeloid leukemia (AML) is still pending. Although hyperexpression of Wilms' tumor (WT1) gene transcript has been frequently proposed as an MRD marker in AML, wide comparability of the various methods used for evaluating WT1 expression has not been given. A standardized, sensitive and universal method for minimal residual disease (MRD) detection in acute myeloid leukemia (AML) is still pending. Although hyperexpression of Wilms' tumor (WT1) gene transcript has been frequently proposed as an MRD marker in AML, wide comparability of the various methods used for evaluating WT1 expression has not been given. (en)
Title	Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study (en)
skos:prefLabel	Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study (en)
skos:notation	RIV/00216208:11130/09:5333!RIV10-MSM-11130___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021620813)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Trka, Jan Kalinová, Markéta
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	343385
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/09:5333
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	WT1 expression; minimal residual disease; real-time PCR; childhood AML; WT1 gene mutations; standardized approach; acute myeloid-leukemia; rt-pcr analysis; polymerase-chain-reaction; quality-control program; myelodysplastic syndromes; prognostic implications; cancer program; bone-marrow; expression; transcripts (en)
http://linked.open.../riv/klicoveSlovo	polymerase-chain-reaction myelodysplastic syndromes expression acute myeloid-leukemia transcripts WT1 expression WT1 gene mutations cancer program childhood AML prognostic implications quality-control program rt-pcr analysis standardized approach bone-marrow real-time PCR minimal residual disease
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[E2726523A631]
http://linked.open...i/riv/nazevZdroje	Leukemia
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	16 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	23
http://linked.open...iv/tvurceVysledku	Reinhardt, D. Trka, Jan Zwaan, CM Weber, G. Biondi, A. Bader, P. Gruhn, B. van der Velden, VHJ Steinbach, D. Kalinová, Markéta Cazzaniga, G. Willasch, A. M. Schneider, G. Coliva, T. Hollink, I. Kreyenberg, H.
http://linked.open...ain/vavai/riv/wos	000268862000015
http://linked.open...n/vavai/riv/zamer	The Molecular Basis of Childhood Malignancies and Therapeutic Applications
issn	0887-6924
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	11130

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