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| rdf:type
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| Description
| - Introduction: The presence of left atrial appendage (LAA) thrombi is the important risk factor for cardioembolic stroke. TEE is recognized as a gold standard for detecting intracardiac thrombi. A noninvasive alternative method would be of clinical value. Aim: To assess the sensitivity, specificity and diagnostic accuracy of 256-multidetector CT (MDCT) angiography in LAA thrombi detection compared to TEE. Methods: 107 patients underwent contrast MDCT for different indications. All patients were simultaneously examined within 7 days by TEE. The presence of LAA thrombi/filling defects were assessed and statistically analyzed. Results: From a total number of 107 patients examined by MDCT the filling defect was found in 11(10.3%) patients. Using the TEE, LAA thrombi were detected in 6(5.6%) patients. With TEE as a reference method the sensitivity of MDCT in LAA thrombi detection was 100% (95 confidence interval [CI]: 56%-100%), specificity 95% (95% CI: 92%-95%) and diagnostic accuracy 95% (95% CI: 90%-95%). The agreement of both methods for the detection of LAA thrombi was high: in 96 patients there were no thrombi detected using MDCT and TEE, in 6 patients there were thrombi found using MDCT and TEE, in 5 patients there were thrombi detected using MDCT but not proven by TEE (kappa = 0.683 [95% CI: 0.344-0.683]). Conclusion: 256-MDCT angiography is a noninvasive imaging method with high sensitivity, specificity and diagnostic accuracy for LAA thrombi detection. In our trial the negative predictive value was 100%. When compared to TEE, MDCT is burdened with radiation exposure and the need of contrast agent.
- Introduction: The presence of left atrial appendage (LAA) thrombi is the important risk factor for cardioembolic stroke. TEE is recognized as a gold standard for detecting intracardiac thrombi. A noninvasive alternative method would be of clinical value. Aim: To assess the sensitivity, specificity and diagnostic accuracy of 256-multidetector CT (MDCT) angiography in LAA thrombi detection compared to TEE. Methods: 107 patients underwent contrast MDCT for different indications. All patients were simultaneously examined within 7 days by TEE. The presence of LAA thrombi/filling defects were assessed and statistically analyzed. Results: From a total number of 107 patients examined by MDCT the filling defect was found in 11(10.3%) patients. Using the TEE, LAA thrombi were detected in 6(5.6%) patients. With TEE as a reference method the sensitivity of MDCT in LAA thrombi detection was 100% (95 confidence interval [CI]: 56%-100%), specificity 95% (95% CI: 92%-95%) and diagnostic accuracy 95% (95% CI: 90%-95%). The agreement of both methods for the detection of LAA thrombi was high: in 96 patients there were no thrombi detected using MDCT and TEE, in 6 patients there were thrombi found using MDCT and TEE, in 5 patients there were thrombi detected using MDCT but not proven by TEE (kappa = 0.683 [95% CI: 0.344-0.683]). Conclusion: 256-MDCT angiography is a noninvasive imaging method with high sensitivity, specificity and diagnostic accuracy for LAA thrombi detection. In our trial the negative predictive value was 100%. When compared to TEE, MDCT is burdened with radiation exposure and the need of contrast agent. (en)
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| Title
| - Detection of left atrial appendage thrombi using multidetector CT-angiography compared with transesophageal echocardiography
- Detection of left atrial appendage thrombi using multidetector CT-angiography compared with transesophageal echocardiography (en)
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| skos:prefLabel
| - Detection of left atrial appendage thrombi using multidetector CT-angiography compared with transesophageal echocardiography
- Detection of left atrial appendage thrombi using multidetector CT-angiography compared with transesophageal echocardiography (en)
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| skos:notation
| - RIV/00216208:11120/14:43908811!RIV15-MSM-11120___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/14:43908811
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Thrombi; Echocardiography; Computed tomography (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Experimental and Clinical Cardiology
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Knot, Jiří
- Widimský, Petr
- Moťovská, Zuzana
- Laboš, Marek
- Petr, Róbert
- Línková, Hana
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
| |
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