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  • Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a research tool for modeling psychosis as well as due to its potential therapeutic effects. However, it is also a very popular and frequently abused natural hallucinogen. This review summarizes all the past and recent knowledge on psilocybin. It briefly deals with its history, discusses the pharmacokinetics and pharmacodynamics, and compares its action in humans and animals. It attempts to describe the mechanism of psychedelic effects and objectify its action using modern imaging and psychometric methods. Finally, it describes its therapeutic and abuse potential.
  • Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a research tool for modeling psychosis as well as due to its potential therapeutic effects. However, it is also a very popular and frequently abused natural hallucinogen. This review summarizes all the past and recent knowledge on psilocybin. It briefly deals with its history, discusses the pharmacokinetics and pharmacodynamics, and compares its action in humans and animals. It attempts to describe the mechanism of psychedelic effects and objectify its action using modern imaging and psychometric methods. Finally, it describes its therapeutic and abuse potential. (en)
Title
  • Psilocybin - Summary of knowledge and new perspectives
  • Psilocybin - Summary of knowledge and new perspectives (en)
skos:prefLabel
  • Psilocybin - Summary of knowledge and new perspectives
  • Psilocybin - Summary of knowledge and new perspectives (en)
skos:notation
  • RIV/00216208:11120/14:43908424!RIV15-MSM-11120___
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  • RIV/00216208:11120/14:43908424
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  • Behavioral studies; Psychological measures; Brain imaging; 5-HT1 receptors; 5-HT2 receptors; Serotonin; Neurobiology; Pharmacology; Hallucinogenic mushrooms; Psychedelics; Hallucinogens; Psilocybin (en)
http://linked.open.../riv/klicoveSlovo
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  • NL - Nizozemsko
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  • [E2907580112A]
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  • European Neuropsychopharmacology
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  • 24
http://linked.open...iv/tvurceVysledku
  • Horáček, Jiří
  • Páleníček, Tomáš
  • Tylš, Filip
http://linked.open...ain/vavai/riv/wos
  • 000333493900002
issn
  • 0924-977X
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.euroneuro.2013.12.006
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  • 11120
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