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  • Background and purpose A reliable and safe diagnostic procedure for vertebral artery (VA) stenosis is needed, but none is generally accepted yet. In our study, we evaluated symptomatic VA stenoses using color Doppler sonography (CDS). CT angiography (CTA) has been employed as a non-invasive reference method. Next, we tested the accuracy for medium to high degree stenoses by digital subtraction angiography (DSA). Materials and methods Sixty-two symptomatic patients with a proximal VA stenosis were examined prospectively with CDS and CTA. The VA diameters by both methods were correlated. The stenotic peak systolic velocity (PSV1) and its ratio to the post-stenotic segment (PSVr) were analysed using receiver operating characteristic curve (ROC). Cut-off values for PSV1 and PSVr defining moderate and severe stenosis were assessed. In stenoses >= 50%, an additional search for correlation with DSA was carried out. Results Mean VA diameter was 3.561 mm (95% CI 3.361–3.760) by CDS and 4.180 (95% CI, 3.950–4.411) by CTA, accompanied with significant similarity in Pearson’ correlation (0.847, P < 0.001). The PSV1 and PSVr appeared to be equally accurate for VA stenoses of 50% or more (PSV 1–AUC 0.814, P < 0.001, cut-off velocity >= 1.35 m/s, PSVr–AUC 0.819, P < 0.001 with a cut-off value >= 2.2). Final Spearman’ correlation of CTA results vs DSA was highly significant (0.823, P < 0.001). Conclusion Our results endorse the non-invasive combination of CDS with CTA in the evaluation of VA stenosis as a reliable diagnostic algorithm, tightly correlating with DSA.
  • Background and purpose A reliable and safe diagnostic procedure for vertebral artery (VA) stenosis is needed, but none is generally accepted yet. In our study, we evaluated symptomatic VA stenoses using color Doppler sonography (CDS). CT angiography (CTA) has been employed as a non-invasive reference method. Next, we tested the accuracy for medium to high degree stenoses by digital subtraction angiography (DSA). Materials and methods Sixty-two symptomatic patients with a proximal VA stenosis were examined prospectively with CDS and CTA. The VA diameters by both methods were correlated. The stenotic peak systolic velocity (PSV1) and its ratio to the post-stenotic segment (PSVr) were analysed using receiver operating characteristic curve (ROC). Cut-off values for PSV1 and PSVr defining moderate and severe stenosis were assessed. In stenoses >= 50%, an additional search for correlation with DSA was carried out. Results Mean VA diameter was 3.561 mm (95% CI 3.361–3.760) by CDS and 4.180 (95% CI, 3.950–4.411) by CTA, accompanied with significant similarity in Pearson’ correlation (0.847, P < 0.001). The PSV1 and PSVr appeared to be equally accurate for VA stenoses of 50% or more (PSV 1–AUC 0.814, P < 0.001, cut-off velocity >= 1.35 m/s, PSVr–AUC 0.819, P < 0.001 with a cut-off value >= 2.2). Final Spearman’ correlation of CTA results vs DSA was highly significant (0.823, P < 0.001). Conclusion Our results endorse the non-invasive combination of CDS with CTA in the evaluation of VA stenosis as a reliable diagnostic algorithm, tightly correlating with DSA. (en)
Title
  • Non-invasive evaluation of proximal vertebral artery stenosis using color Doppler sonography and CT angiography
  • Non-invasive evaluation of proximal vertebral artery stenosis using color Doppler sonography and CT angiography (en)
skos:prefLabel
  • Non-invasive evaluation of proximal vertebral artery stenosis using color Doppler sonography and CT angiography
  • Non-invasive evaluation of proximal vertebral artery stenosis using color Doppler sonography and CT angiography (en)
skos:notation
  • RIV/00216208:11120/14:43907978!RIV15-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, S
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 32764
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/14:43907978
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Non-invasive evaluation; Vertebral artery proximal stenosis; Digital subtraction angiography; CT angiography; Color Doppler sonography (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • FR - Francouzská republika
http://linked.open...ontrolniKodProRIV
  • [CE5099C3EC9B]
http://linked.open...i/riv/nazevZdroje
  • Journal of Neuroradiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 41
http://linked.open...iv/tvurceVysledku
  • Škoda, Ondřej
  • Procházka, Bohumír
  • Kalvach, Pavel
http://linked.open...ain/vavai/riv/wos
  • 000346550100007
issn
  • 0150-9861
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.neurad.2013.11.003
http://localhost/t...ganizacniJednotka
  • 11120
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