About: Adaptation of human adipose tissue to hypocaloric diet

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Hypocaloric diet is a key component of the weight-reducing treatment of obesity and obesity-related disorders. Hypocaloric diets and the associated weight reduction promote improvement of metabolic profile of obese individuals. Among the mechanisms that underlie this beneficial metabolic outcome, the diet-induced modifications of morphological and functional characteristics of human adipose tissue (AT) are believed to have an important role. Prospective studies of hypocaloric weight-reducing dietary intervention demonstrate effects on adipocyte metabolism, namely lipolysis and lipogenesis, and associated changes of the adipocyte size. The endocrine function of AT, which involves cytokine and adipokine production by adipocytes, as well as by cells of stromavascular fraction, is also regulated by dietary intervention. Related inflammatory status of AT is modulated also as a consequence of the changes in recruitment of immune cells, mainly macrophages, in AT. Here, we give an overview of metabolic and endocrine modifications in human AT induced by a variety of hypocaloric diets. Hypocaloric diet is a key component of the weight-reducing treatment of obesity and obesity-related disorders. Hypocaloric diets and the associated weight reduction promote improvement of metabolic profile of obese individuals. Among the mechanisms that underlie this beneficial metabolic outcome, the diet-induced modifications of morphological and functional characteristics of human adipose tissue (AT) are believed to have an important role. Prospective studies of hypocaloric weight-reducing dietary intervention demonstrate effects on adipocyte metabolism, namely lipolysis and lipogenesis, and associated changes of the adipocyte size. The endocrine function of AT, which involves cytokine and adipokine production by adipocytes, as well as by cells of stromavascular fraction, is also regulated by dietary intervention. Related inflammatory status of AT is modulated also as a consequence of the changes in recruitment of immune cells, mainly macrophages, in AT. Here, we give an overview of metabolic and endocrine modifications in human AT induced by a variety of hypocaloric diets. (en)
Title	Adaptation of human adipose tissue to hypocaloric diet Adaptation of human adipose tissue to hypocaloric diet (en)
skos:prefLabel	Adaptation of human adipose tissue to hypocaloric diet Adaptation of human adipose tissue to hypocaloric diet (en)
skos:notation	RIV/00216208:11120/13:43903621!RIV14-MZ0-11120___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NS10519), P(NT11450), Z(MSM0021620814)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Rossmeislová, Lenka Štich, Vladimír Mališová, Lucia Kračmerová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	59466
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/13:43903621
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	macrophages; adipokines; adipose tissue metabolism; hypocaloric diet; human obesity (en)
http://linked.open.../riv/klicoveSlovo	adipose tissue metabolism human obesity hypocaloric diet macrophages adipokines
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[EBAA989671B0]
http://linked.open...i/riv/nazevZdroje	International Journal of Obesity
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Endocrine and metabolic characteristics of gluteal subcutaneous adipose tissue and its relationship to indicators of metabolic syndrome Relative abundance of macrophages and other cell populations in adipose tissue in relation to obesity and associated metabolic complications
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	37
http://linked.open...iv/tvurceVysledku	Štich, Vladimír Rossmeislová, Lenka Kračmerová, Jana Mališová, Lucia
http://linked.open...ain/vavai/riv/wos	000318772400003
http://linked.open...n/vavai/riv/zamer	Prevention, diagnostics and therapy of diabetes mellitus, metabolic and endocrine damage of organism
issn	0307-0565
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1038/ijo.2012.80
http://localhost/t...ganizacniJednotka	11120

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