About: The effects of beta-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:seeAlso
Description
  • The purpose of this study was to evaluate the effect of beta-(1,3/1,6)-d-glucan isolated from Pleurotus ostreatus (beta-glucan-PO) on prophylactic treatment of adjuvant arthritis (AA) with methotrexate (MTX) in rats. Groups of rats with AA were treated with methotrexate (1 mg/kg/week), beta-glucan-PO (1 mg/kg every second day) or their combination for the period of 28 days from adjuvant application. Body mass, hind paw swelling, arthrogram scores and a level of serum albumin were measured as markers of inflammation and arthritis. Treatment with low dose of MTX significantly inhibited the markers of both inflammation and arthritis. MTX and its combination with beta-glucan-PO significantly increased body mass of arthritic rats. beta-glucan-PO administered alone significantly decreased both the hind paw swelling and arthritic score. In combination with MTX, beta-glucan-PO markedly potentiated the beneficial effects of MTX, which resulted in a more significant reduction of hind paw swelling and arthritic
  • The purpose of this study was to evaluate the effect of beta-(1,3/1,6)-d-glucan isolated from Pleurotus ostreatus (beta-glucan-PO) on prophylactic treatment of adjuvant arthritis (AA) with methotrexate (MTX) in rats. Groups of rats with AA were treated with methotrexate (1 mg/kg/week), beta-glucan-PO (1 mg/kg every second day) or their combination for the period of 28 days from adjuvant application. Body mass, hind paw swelling, arthrogram scores and a level of serum albumin were measured as markers of inflammation and arthritis. Treatment with low dose of MTX significantly inhibited the markers of both inflammation and arthritis. MTX and its combination with beta-glucan-PO significantly increased body mass of arthritic rats. beta-glucan-PO administered alone significantly decreased both the hind paw swelling and arthritic score. In combination with MTX, beta-glucan-PO markedly potentiated the beneficial effects of MTX, which resulted in a more significant reduction of hind paw swelling and arthritic (en)
Title
  • The effects of beta-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis
  • The effects of beta-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis (en)
skos:prefLabel
  • The effects of beta-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis
  • The effects of beta-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis (en)
skos:notation
  • RIV/00216208:11120/11:00003404!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 196604
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/11:00003404
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • beta-Glucan; Methotrexate; Adjuvant arthritis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [D5B545C58DCA]
http://linked.open...i/riv/nazevZdroje
  • Rheumatology International
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 31
http://linked.open...iv/tvurceVysledku
  • Jurčovičová, Jana
  • Rovenský, Jozef
http://linked.open...ain/vavai/riv/wos
  • 000288508500011
issn
  • 0172-8172
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00296-009-1258-z
http://localhost/t...ganizacniJednotka
  • 11120
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 75 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software