About: Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women

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About: Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.medscimonit.com/fulltxt.php?ICID=882048
Description	Endothelial dysfunction and postprandial hyperglycemia represent independent risk factors for cardiovascular diseases. Obesity is connected with endothelial impairments; however, it is unclear whether weight loss can modify endothelial function during the postprandial period. The aim of this study was to evaluate endothelial response (post-ischemic forearm blood flow, PIFBF) in a fasted state and following ingestion of 75 g glucose before and after very low caloric diet (VLCD). 40 obese premenopausal women (age 39.6- 7.8 years, BMI 34.3-3.2 kg/m2) participated in 4-week very low caloric diet (VLCD, 800 kcal/day). Before and after VLCD, the baseline blood flow and PIFBF were measured using a mercury strain gauge plethysmography in fasting state as well as 1 hour after ingestion of 75 g glucose. Dietary intervention resulted in a 7% weight loss (p<0.05) and a decrease in insulin resistance index HOMA-IR (2.44-1.25 vs. 1.66-0.81, p<0.05). Before VLCD intervention, PIFBF following oral glucose chall Endothelial dysfunction and postprandial hyperglycemia represent independent risk factors for cardiovascular diseases. Obesity is connected with endothelial impairments; however, it is unclear whether weight loss can modify endothelial function during the postprandial period. The aim of this study was to evaluate endothelial response (post-ischemic forearm blood flow, PIFBF) in a fasted state and following ingestion of 75 g glucose before and after very low caloric diet (VLCD). 40 obese premenopausal women (age 39.6- 7.8 years, BMI 34.3-3.2 kg/m2) participated in 4-week very low caloric diet (VLCD, 800 kcal/day). Before and after VLCD, the baseline blood flow and PIFBF were measured using a mercury strain gauge plethysmography in fasting state as well as 1 hour after ingestion of 75 g glucose. Dietary intervention resulted in a 7% weight loss (p<0.05) and a decrease in insulin resistance index HOMA-IR (2.44-1.25 vs. 1.66-0.81, p<0.05). Before VLCD intervention, PIFBF following oral glucose chall (en)
Title	Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women (en)
skos:prefLabel	Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women (en)
skos:notation	RIV/00216208:11120/11:00003205!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita	R
http://linked.open...avai/riv/aktivity	R
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Bajzová, Magda Štich, Vladimír Wedellová, Zuzana Šiklová-Vítková, Michaela Polák, Jan Hašpicová, Marcela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	221937
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/11:00003205
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	endothelial dysfunction; weight loss; atherosclerosis; forearm pletysmography (en)
http://linked.open.../riv/klicoveSlovo	endothelial dysfunction atherosclerosis forearm pletysmography weight loss
http://linked.open...odStatuVydavatele	PL - Polská republika
http://linked.open...ontrolniKodProRIV	[FE35685819AD]
http://linked.open...i/riv/nazevZdroje	Medical Science Monitor
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	17
http://linked.open...iv/tvurceVysledku	Polák, Jan Wedellová, Zuzana Šiklová-Vítková, Michaela Štich, Vladimír Bajzová, Magda Hejnová, Jindřiška Hašpicová, Marcela
http://linked.open...ain/vavai/riv/wos	000298036400020
issn	1234-1010
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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