About: Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)

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About: Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST) Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.signavitae.com/articles/original-articles/178-targeting-out-of-hospital-cardiac-arrest-the-effect-of-heparin-administered-during-cardiopulmonary-resuscitation-t-arrest
Description	Heparin administration during cardiopulmonary resuscitation (CPR) may prevent activation of coagulation after successful resuscitation for out-of-hospital cardiac arrest (OHCA). We hypothesize that such an approach is not associated with an increased rate of bleeding, but it has not been evaluated. We performed a pilot randomized clinical study assessing the safety of intra-arrest heparin administration in OHCA patients with suspected acute myocardial infarction (AMI) and its impact on their prognosis. OHCA patients were randomized during CPR to 10 000 units of intra-arrest intravenous heparin (Group H) or to treatment without heparin (Group C). The occurrence of major bleeding and the presence of a favourable neurological result 3 months after OHCA, were analyzed. Out of 88 randomized patients, AMI was subsequently confirmed in 63 of them (71.6 %). There were 30 patients in group H and 33 in group C. No major bleeding event was observed in either group. Heparin administration during cardiopulmonary resuscitation (CPR) may prevent activation of coagulation after successful resuscitation for out-of-hospital cardiac arrest (OHCA). We hypothesize that such an approach is not associated with an increased rate of bleeding, but it has not been evaluated. We performed a pilot randomized clinical study assessing the safety of intra-arrest heparin administration in OHCA patients with suspected acute myocardial infarction (AMI) and its impact on their prognosis. OHCA patients were randomized during CPR to 10 000 units of intra-arrest intravenous heparin (Group H) or to treatment without heparin (Group C). The occurrence of major bleeding and the presence of a favourable neurological result 3 months after OHCA, were analyzed. Out of 88 randomized patients, AMI was subsequently confirmed in 63 of them (71.6 %). There were 30 patients in group H and 33 in group C. No major bleeding event was observed in either group. (en)
Title	Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST) Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST) (en)
skos:prefLabel	Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST) Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST) (en)
skos:notation	RIV/00216208:11120/11:00003192!RIV12-MZ0-11120___
http://linked.open...avai/riv/aktivita	I P S Z
http://linked.open...avai/riv/aktivity	I, P(NR7970), P(NS10383), S, Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Málek, J. Waldauf, Petr Knor, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	234218
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/11:00003192
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	heparin; major bleeding; out-of-hospital cardiac arrest (en)
http://linked.open.../riv/klicoveSlovo	out-of-hospital cardiac arrest major bleeding heparin
http://linked.open...odStatuVydavatele	HR - Chorvatská republika
http://linked.open...ontrolniKodProRIV	[EBB775724FED]
http://linked.open...i/riv/nazevZdroje	Signa Vitae
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	New therapeutic procedures during cardiopulmonary resuscitation in animal model of ventricular fibrillation Sudden Cardiac arrest in out-of-hospital care. Analysis of causes and comparison of different methods recommended for circulatory restoration.
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	6
http://linked.open...iv/tvurceVysledku	Málek, Jiří Waldauf, Petr Knor, Jiří
http://linked.open...ain/vavai/riv/wos	000298179500003
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	1334-5605
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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