About: The effect of methamphetamine on social interaction of adult male rats

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The effect of psychostimulants on social behavior still remains unclear. Therefore the aim of the present study was to assess the effect of low doses of methamphetamine (MA) on social interaction (SI) in adult male rats. Rats were tested in three environmental conditions: (1) dimly lit, familiar environment, (2) dimly lit, unfamiliar environment and (3) intensely lit, unfamiliar environment considered to be low, middle and high stress, respectively. In each condition different set of animals was used. Rats were always divided into five groups. Control (without injection), saline (with 1 ml/kg saline injection) and three MA groups (doses: 0.5, 1 and 1.5mg/kg). Injections were applied 30 min prior to testing. Always a pair of unfamiliar rats of the same treatment group was tested. Their behavior was video recorded for 5 min in an open field. Times spent by SI (following, climbing, genital investigation, etc.) and non-social behavior (locomotion, rearing) were analyzed using a two-way ANOVA (drug treatme The effect of psychostimulants on social behavior still remains unclear. Therefore the aim of the present study was to assess the effect of low doses of methamphetamine (MA) on social interaction (SI) in adult male rats. Rats were tested in three environmental conditions: (1) dimly lit, familiar environment, (2) dimly lit, unfamiliar environment and (3) intensely lit, unfamiliar environment considered to be low, middle and high stress, respectively. In each condition different set of animals was used. Rats were always divided into five groups. Control (without injection), saline (with 1 ml/kg saline injection) and three MA groups (doses: 0.5, 1 and 1.5mg/kg). Injections were applied 30 min prior to testing. Always a pair of unfamiliar rats of the same treatment group was tested. Their behavior was video recorded for 5 min in an open field. Times spent by SI (following, climbing, genital investigation, etc.) and non-social behavior (locomotion, rearing) were analyzed using a two-way ANOVA (drug treatme (en)
Title	The effect of methamphetamine on social interaction of adult male rats The effect of methamphetamine on social interaction of adult male rats (en)
skos:prefLabel	The effect of methamphetamine on social interaction of adult male rats The effect of methamphetamine on social interaction of adult male rats (en)
skos:notation	RIV/00216208:11120/10:00002409!RIV11-GA0-11120___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0517), P(GAP303/10/0580), Z(MSM0021620816)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Mikulecká, Anna Schutová, Barbora Pometlová, Marie Hrubá, Lenka Šlamberová, Romana Deykun, Kateryna
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	256058
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/10:00002409
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Methamphetamine; social behavior; stress environment condition (en)
http://linked.open.../riv/klicoveSlovo	stress environment condition social behavior Methamphetamine
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[F14FFCB62E89]
http://linked.open...i/riv/nazevZdroje	Behavioural Brain Research
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of Neuropsychiatric Studies 2005-2009 (Neurobiology in Clinical Application) What is the role of mesolimbic reward circuit in the long-term effect of prenatal methamphetamine exposure in rats?
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	214
http://linked.open...iv/tvurceVysledku	Mikulecká, Anna Hrubá, Lenka Pometlová, Marie Schutová, Barbora Šlamberová, Romana Deykun, Kateryna
http://linked.open...ain/vavai/riv/wos	000281318700034
http://linked.open...n/vavai/riv/zamer	Název: Patofyziologie neuropsychiatrických onemocnění a její klinické aplikace
issn	0166-4328
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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