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  • We studied the course of major mood disorders in the offspring of parents with well-characterised bipolar disorder prospectively for up to 15 years. All consenting offspring were assessed annually or anytime symptomatic. The participants began to develop major mood episodes in adolescence and not before. The index major mood episode was almost always depressive, as were the first few recurrences. onsets and recurrences continued throughout the observation period into adulthood. We did not find evidence of pre-pubertal mania. in summary, adolescence marks the beginning of the high-risk period for major mood episodes related to bipolar disorder.
  • We studied the course of major mood disorders in the offspring of parents with well-characterised bipolar disorder prospectively for up to 15 years. All consenting offspring were assessed annually or anytime symptomatic. The participants began to develop major mood episodes in adolescence and not before. The index major mood episode was almost always depressive, as were the first few recurrences. onsets and recurrences continued throughout the observation period into adulthood. We did not find evidence of pre-pubertal mania. in summary, adolescence marks the beginning of the high-risk period for major mood episodes related to bipolar disorder. (en)
Title
  • Early course of bipolar disorder in high-risk offspring: prospective study
  • Early course of bipolar disorder in high-risk offspring: prospective study (en)
skos:prefLabel
  • Early course of bipolar disorder in high-risk offspring: prospective study
  • Early course of bipolar disorder in high-risk offspring: prospective study (en)
skos:notation
  • RIV/00216208:11120/09:43906859!RIV13-MSM-11120___
http://linked.open...avai/riv/aktivita
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  • N, V
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  • 5
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  • 311762
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  • RIV/00216208:11120/09:43906859
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  • Parents; Episodes; Schedule; Schizophrenia; Children (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [DD076E6E0B55]
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  • British Journal of Psychiatry
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  • 195
http://linked.open...iv/tvurceVysledku
  • Alda, Martin
  • Hájek, Tomáš
http://linked.open...ain/vavai/riv/wos
  • 000272274100013
issn
  • 0007-1250
number of pages
http://bibframe.org/vocab/doi
  • 10.1192/bjp.bp.108.062810
http://localhost/t...ganizacniJednotka
  • 11120
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