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  • The invasion of extravillous trophoblast cells into the maternal endometrium is one of the key events in human placentation. The ability of these cells to infiltrate the uterine wall and to anchor the placenta to it as well as their ability to infiltrate and adjust utero-placental vessels to pregnancy depends, among other things, on their ability to secrete enzymes that degrade the extracellular matrix. Most of these enzymes belong to the family of matrix metal loproteinases. Matrix metal loproteinases (MMPs) belong to secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. This assay can be used in detecting MMP activity in biological samples using a EDANS/DABCYL fluorescence resonance energy transfer (FRET) peptide.
  • The invasion of extravillous trophoblast cells into the maternal endometrium is one of the key events in human placentation. The ability of these cells to infiltrate the uterine wall and to anchor the placenta to it as well as their ability to infiltrate and adjust utero-placental vessels to pregnancy depends, among other things, on their ability to secrete enzymes that degrade the extracellular matrix. Most of these enzymes belong to the family of matrix metal loproteinases. Matrix metal loproteinases (MMPs) belong to secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. This assay can be used in detecting MMP activity in biological samples using a EDANS/DABCYL fluorescence resonance energy transfer (FRET) peptide. (en)
Title
  • Detection of MMP-2 and MMP-9 in Normal Uncomplicated Pregnancy
  • Detection of MMP-2 and MMP-9 in Normal Uncomplicated Pregnancy (en)
skos:prefLabel
  • Detection of MMP-2 and MMP-9 in Normal Uncomplicated Pregnancy
  • Detection of MMP-2 and MMP-9 in Normal Uncomplicated Pregnancy (en)
skos:notation
  • RIV/00216208:11120/08:00002131!RIV11-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 362826
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/08:00002131
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Collagenase; expression; invasion; uterus (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [48752185ED75]
http://linked.open...v/mistoKonaniAkce
  • Athens
http://linked.open...i/riv/mistoVydani
  • Bologna
http://linked.open...i/riv/nazevZdroje
  • Proceedings of the 20th International Congress in Thrombosis
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Měchurová, Alena
http://linked.open...vavai/riv/typAkce
http://linked.open...ain/vavai/riv/wos
  • 000263469000010
http://linked.open.../riv/zahajeniAkce
number of pages
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  • Medimond
https://schema.org/isbn
  • 978-88-7587-423-0
http://localhost/t...ganizacniJednotka
  • 11120
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