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rdf:type
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Description
| - Colorectal cancer represents a complex disease where susceptibility may be influenced by genetic polymorphisms in the DNA repair system. In the present study we investigated the role of nine single nucleotide polymorphisms in eight DNA repair genes on the risk of colorectal cancer in a hospital-based case-control population (532 cases and 532 sex- and age-matched controls). Data analysis showed that the variant allele homozygotes for the Asn148Glu polymorphism in the APE1 gene were at a statistically non-significant increased risk of colorectal cancer
- Colorectal cancer represents a complex disease where susceptibility may be influenced by genetic polymorphisms in the DNA repair system. In the present study we investigated the role of nine single nucleotide polymorphisms in eight DNA repair genes on the risk of colorectal cancer in a hospital-based case-control population (532 cases and 532 sex- and age-matched controls). Data analysis showed that the variant allele homozygotes for the Asn148Glu polymorphism in the APE1 gene were at a statistically non-significant increased risk of colorectal cancer (en)
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Title
| - DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic
- DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic (en)
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skos:prefLabel
| - DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic
- DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic (en)
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skos:notation
| - RIV/00216208:11120/08:00001636!RIV10-MZ0-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA310/05/2626), P(NR8563), R, S, Z(AV0Z50390512), Z(MSM0021620808)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/08:00001636
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - colorectal cancer; individual susceptibility; DNA repair; single-nucleotide polymorphisms; case-control study (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Barale, R.
- Hemminki, K.
- Novotný, J.
- Vodička, Pavel
- Vodičková, Ludmila
- Šmerhovský, Zdeněk
- Poláková, Veronika
- Kumar, R.
- Naccarati, A.
- Pardini, B.
- Bortlík, M.
- Tulupová, E.
- Hánová, M.
- Slyšková, J.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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