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Description
| - Our previous studies demonstrated that methamphetamine (MA) administered during gestation and lactation periods impairs maternal behavior as well as the postnatal development of rat pups. The present study tested the hypothesis that the cross-fostering influences the development of rat pups. Mothers were daily exposed to injection of MA (5 mg/kg) and saline for 9 weeks: three weeks prior to impregnation, throughout the entire gestation period and during lactation. As a control (C) females with no injections were used. On postnatal day (PD 1), pups were cross-fostered so that each mother received some of her own and some of the pups of mother with the other treatments. Pup's development and sensorimotor coordination was examined between PD 1 and PD 23. Following tests were used: tail pull (PD 10), righting reflex on surface (PD 12), righting reflex on mid-air (PD 17) and rotarod (PD 23). Our results showed that the birth weight in prenatally MA-exposed pups was lower than controls or saline-expose
- Our previous studies demonstrated that methamphetamine (MA) administered during gestation and lactation periods impairs maternal behavior as well as the postnatal development of rat pups. The present study tested the hypothesis that the cross-fostering influences the development of rat pups. Mothers were daily exposed to injection of MA (5 mg/kg) and saline for 9 weeks: three weeks prior to impregnation, throughout the entire gestation period and during lactation. As a control (C) females with no injections were used. On postnatal day (PD 1), pups were cross-fostered so that each mother received some of her own and some of the pups of mother with the other treatments. Pup's development and sensorimotor coordination was examined between PD 1 and PD 23. Following tests were used: tail pull (PD 10), righting reflex on surface (PD 12), righting reflex on mid-air (PD 17) and rotarod (PD 23). Our results showed that the birth weight in prenatally MA-exposed pups was lower than controls or saline-expose (en)
- Prenatální expozice metamfetaminu negativně ovlivňuje mateřské chování a postnatální vývoj mláďat. Naše nejnovější poznatky ukazují, že zpoždění ve vývoji senzorimotorických funkcí je možné ovlivnit výchovou adoptivní kontrolní matkou. (cs)
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Title
| - Does cross-fostering modify the impairing effect of methamphetamine on postnatal development of rat pups?
- Ovlivní %22cross-fostering%22 negativní vliv metamfetaminu na postnatální vývoj potkaních mláďat? (cs)
- Does cross-fostering modify the impairing effect of methamphetamine on postnatal development of rat pups? (en)
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skos:prefLabel
| - Does cross-fostering modify the impairing effect of methamphetamine on postnatal development of rat pups?
- Ovlivní %22cross-fostering%22 negativní vliv metamfetaminu na postnatální vývoj potkaních mláďat? (cs)
- Does cross-fostering modify the impairing effect of methamphetamine on postnatal development of rat pups? (en)
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skos:notation
| - RIV/00216208:11120/08:00000846!RIV09-MZ0-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1A8610), Z(MSM0021620816)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/08:00000846
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Methamphetamine; Development; Senzorimotor; Cross-fostering (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hrubá, Lenka
- Pometlová, Marie
- Schutová, Barbora
- Šlamberová, Romana
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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