| Attributes | Values |
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| rdf:type
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| Description
| - Adiponectin zvyšuje inzulínovou citlivost a chrání stěnu cévní před aterosklerózou. Hladiny jsou snížené u obézních, inzulinorezistentních a diebtických pacientů. V plazmě existuje adiponectin jako vysoko, středně a nízkomolekulární forma (HMW, MMW, and LMW). SUBJEKTY: 22 obézních žen s nejvyšší a 20 obézních žen s nejnižším zlepšením inzulínové senzitivity po dietní intervenci (respondérky a non-respondérky), (body mass index (BMI)=34.5 (s.d. 2.9) resp. 36.5 kg/m(2) (s.d. 4.0) bylo vybráno z 292 žen, které podstoupily 10-týdenní nízkokalorickou dietu (LCD). Hladina plazmatického HMW, MMW, a LMW a celkového adiponectinu baly změřena Western blottingem. Výsledky: LCD indukovala identickou redukci hmotnosti v obou skupinách o 8.2 a 7.6 kg. HOMA index poklesl o Homeostasis 48.1% u respondérek a zůstal nezměněn u non-respondérek. Celkový adiponectin i jeho polymerní izoformy zůstaly u obou skupin beze změny (pouze LMW se zvýšil o 16.3% u non-respondérek).Závěry: Adiponectin není významným determina (cs)
- AIM: Adiponectin increases insulin sensitivity, protects arterial walls against atherosclerosis, and regulates glucose metabolism, and is decreased in obese, insulin resistant, and type 2 diabetic patients. Adiponectin circulates in plasma as high, medium, and low molecular weight forms (HMW, MMW, and LMW). The HMW form was suggested to be closely associated with insulin sensitivity. This study investigated whether diet-induced changes in insulin sensitivity were associated with changes in adiponectin multimeric complexes. SUBJECTS: Twenty obese women with highest and twenty obese women with lowest diet induced changes in insulin sensitivity (responders and non-responders respectively), matched for weight loss (body mass index (BMI)=34.5 (s.d. 2.9) resp. 36.5 kg/m(2) (s.d. 4.0) for responders and non-responders), were selected from 292 women who underwent a 10-week low-caloric diet (LCD; 600 kcal/d less than energy requirements). Plasma HMW, MMW, and LMW forms of adiponectin were quantified using West
- AIM: Adiponectin increases insulin sensitivity, protects arterial walls against atherosclerosis, and regulates glucose metabolism, and is decreased in obese, insulin resistant, and type 2 diabetic patients. Adiponectin circulates in plasma as high, medium, and low molecular weight forms (HMW, MMW, and LMW). The HMW form was suggested to be closely associated with insulin sensitivity. This study investigated whether diet-induced changes in insulin sensitivity were associated with changes in adiponectin multimeric complexes. SUBJECTS: Twenty obese women with highest and twenty obese women with lowest diet induced changes in insulin sensitivity (responders and non-responders respectively), matched for weight loss (body mass index (BMI)=34.5 (s.d. 2.9) resp. 36.5 kg/m(2) (s.d. 4.0) for responders and non-responders), were selected from 292 women who underwent a 10-week low-caloric diet (LCD; 600 kcal/d less than energy requirements). Plasma HMW, MMW, and LMW forms of adiponectin were quantified using West (en)
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| Title
| - Total adiponectin and adiponectin multimeric complexes in relation to weight loss-induced improvements in insulin sensitivity in obese women: the NUGENOB study
- Celkový adiponectin a jeho polymerní izoformy ve vztahu k redukci hmotnosti a zlepšené inzulínové citlivosti u obézních žen, studie NUGENOB (cs)
- Total adiponectin and adiponectin multimeric complexes in relation to weight loss-induced improvements in insulin sensitivity in obese women: the NUGENOB study (en)
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| skos:prefLabel
| - Total adiponectin and adiponectin multimeric complexes in relation to weight loss-induced improvements in insulin sensitivity in obese women: the NUGENOB study
- Celkový adiponectin a jeho polymerní izoformy ve vztahu k redukci hmotnosti a zlepšené inzulínové citlivosti u obézních žen, studie NUGENOB (cs)
- Total adiponectin and adiponectin multimeric complexes in relation to weight loss-induced improvements in insulin sensitivity in obese women: the NUGENOB study (en)
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| skos:notation
| - RIV/00216208:11120/08:00000691!RIV09-MSM-11120___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/08:00000691
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - adiponectin; obesity; diet; weight loss; insulin sensitivity (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - European Journal of Endocrinology
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Kováčová, Zuzana
- Polák, Jan
- Štich, Vladimír
- Patel, K.
- Astrup, A.
- Langin, D.
- Oppert, J. M.
- Holst, C.
- Martinez, J. A
- Verdich, C.
- Blaak, E.
- Sorensen, T. I.
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| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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