About: Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease     Goto   Sponge   NotDistinct   Permalink

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Description
  • Menièrova choroba je idiopatické nitroušní onemocnění charakterizované kolísavou ztrátou sluchu, občasným vertigem a tinnitem (cs)
  • Ménière's disease (MD) is an idiopathic inner-ear disorder characterized by fluctuating hearing loss, episodic vertigo, and tinnitus. Though MD's etiology is unknown, growing evidence suggests that autoimmunity may be involved in its development. The aim of this prospective study was to investigate the presence of anti-heat shock protein 70 (anti-HSP70) antibodies during the acute phase of MD and to relate its presence to the antibody pattern. We examined the sera of 13 patients by Western blot immunoassays for reactivity to bovine inner-ear antigen (anti-HSP70) antibodies. The presence of viral antibodies and autoantibodies (herpes simplex, types 1, 2; herpes zoster; cytomegalovirus; Epstein-Barr; IgM; IgG; cardiolipin; thyroglobulin and thyroperoxidase; and antinuclear, antimitochondrial, and anti-smooth-cell antibodies) were also tested. We found reactivity to HSP70 in only 1 of the 13 MD patients (7.7%), and it occurred during herpes zoster reactivation. We found no relationship bet
  • Ménière's disease (MD) is an idiopathic inner-ear disorder characterized by fluctuating hearing loss, episodic vertigo, and tinnitus. Though MD's etiology is unknown, growing evidence suggests that autoimmunity may be involved in its development. The aim of this prospective study was to investigate the presence of anti-heat shock protein 70 (anti-HSP70) antibodies during the acute phase of MD and to relate its presence to the antibody pattern. We examined the sera of 13 patients by Western blot immunoassays for reactivity to bovine inner-ear antigen (anti-HSP70) antibodies. The presence of viral antibodies and autoantibodies (herpes simplex, types 1, 2; herpes zoster; cytomegalovirus; Epstein-Barr; IgM; IgG; cardiolipin; thyroglobulin and thyroperoxidase; and antinuclear, antimitochondrial, and anti-smooth-cell antibodies) were also tested. We found reactivity to HSP70 in only 1 of the 13 MD patients (7.7%), and it occurred during herpes zoster reactivation. We found no relationship bet (en)
Title
  • Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease
  • Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease (en)
  • Virová infekce a sérové protilátky proti 'heat shock protein 70' v akutní fázi Meniérovy choroby (cs)
skos:prefLabel
  • Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease
  • Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease (en)
  • Virová infekce a sérové protilátky proti 'heat shock protein 70' v akutní fázi Meniérovy choroby (cs)
skos:notation
  • RIV/00216208:11120/07:00001013!RIV09-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 457957
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/07:00001013
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • anti heat shock protein 70 antibodies; autoantibodies; cytomegalovirus; herpes-virus; Meniére's disease (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [31C38B20A625]
http://linked.open...i/riv/nazevZdroje
  • International Tinnitus Journal
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 13
http://linked.open...iv/tvurceVysledku
  • Hahn, Aleš
  • Alpini, D.
  • Cesarani, A.
  • Di Berardino, F.
issn
  • 0946-5448
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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