About: Blood metallothionein, neuron specific enolase, and protein S100B in patients with traumatic brain injury

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About: Blood metallothionein, neuron specific enolase, and protein S100B in patients with traumatic brain injury Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of this study was to evaluate the correlation of neuron specific enolase (NSE), protein S100B and time-profile of Glasgow Coma Score (GCS) development with metallothionein (MT) blood levels in patients with traumatic brain injury (TBI) during 10 days of hospitalization. Patients were divided into 2 groups with respect to NSE and S100B levels-with (group 1) and without (group II) GCS improvement. RESULTS: Values of MT in the blood of group I showed a non-significant decrease compared to group II during 1-3 days after admission. There was an increase of MT during 4-8 days in comparison with values of 1-3 days. The highest value of MT during hospitalization was found in a patient with diffuse axonal injury (group 11). The data of cDNA microarray suggested an increase in expression of gene transcripts for oxygen free radical scavenger proteins corresponding with the increase of MT during 4-8 days in both groups. CONCLUSIONS: The experimental data indicate that monitoring the content of MT in pati The aim of this study was to evaluate the correlation of neuron specific enolase (NSE), protein S100B and time-profile of Glasgow Coma Score (GCS) development with metallothionein (MT) blood levels in patients with traumatic brain injury (TBI) during 10 days of hospitalization. Patients were divided into 2 groups with respect to NSE and S100B levels-with (group 1) and without (group II) GCS improvement. RESULTS: Values of MT in the blood of group I showed a non-significant decrease compared to group II during 1-3 days after admission. There was an increase of MT during 4-8 days in comparison with values of 1-3 days. The highest value of MT during hospitalization was found in a patient with diffuse axonal injury (group 11). The data of cDNA microarray suggested an increase in expression of gene transcripts for oxygen free radical scavenger proteins corresponding with the increase of MT during 4-8 days in both groups. CONCLUSIONS: The experimental data indicate that monitoring the content of MT in pati (en)
Title	Blood metallothionein, neuron specific enolase, and protein S100B in patients with traumatic brain injury Blood metallothionein, neuron specific enolase, and protein S100B in patients with traumatic brain injury (en)
skos:prefLabel	Blood metallothionein, neuron specific enolase, and protein S100B in patients with traumatic brain injury Blood metallothionein, neuron specific enolase, and protein S100B in patients with traumatic brain injury (en)
skos:notation	RIV/00216208:11120/06:00002212!RIV11-MZ0-11120___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR8793)
http://linked.open...iv/cisloPeriodika	Suppl. 2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Šámal, Filip Haninec, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	467203
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/06:00002212
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	metallothionein; contusion; diffuse axonal injury; Glasgow Coma Score; neuron specific enolase; S100B protein; oxidative stress; Brdicka reaction; differential pulse voltammetry (en)
http://linked.open.../riv/klicoveSlovo	S100B protein oxidative stress differential pulse voltammetry metallothionein diffuse axonal injury Brdicka reaction contusion neuron specific enolase Glasgow Coma Score
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[C30650326CCD]
http://linked.open...i/riv/nazevZdroje	Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Biochemical diagnosis of expansive and consequently colorating contusions by patients with trauma of head
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	27
http://linked.open...iv/tvurceVysledku	Kukačka, Jiří Houšťava, Ladislav Šámal, Filip
http://linked.open...ain/vavai/riv/wos	000245442600028
issn	0172-780X
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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