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Description
| - Práce popisuje randomizovanou kontrolovano studii autologních transplantací hematopoetických kmenových buněk pro autoimunitní onemocnění (cs)
- Hematologists/oncologists initiated the use of autologous hematopoietic stem cell transplantation. (HSCT) as a treatment for severe autoimmune diseases beginning in the early 1990s. According to multicenter reports, this therapy has been plagued by a high rate of transplant-related mortality. However, transplantrelated mortality from different individual centers varies widely. We will review and discuss how the differences in philosophy, rationale, and design of these protocols affect treatment-related mortality, and we will compare how these differences have influenced ongoing or soonto-be-opened randomized controlled trials of autologous HSCT for patients with autoimmune diseases. In particular, we will emphasize the distinction between myeloablative and lymphoablative trials
- Hematologists/oncologists initiated the use of autologous hematopoietic stem cell transplantation. (HSCT) as a treatment for severe autoimmune diseases beginning in the early 1990s. According to multicenter reports, this therapy has been plagued by a high rate of transplant-related mortality. However, transplantrelated mortality from different individual centers varies widely. We will review and discuss how the differences in philosophy, rationale, and design of these protocols affect treatment-related mortality, and we will compare how these differences have influenced ongoing or soonto-be-opened randomized controlled trials of autologous HSCT for patients with autoimmune diseases. In particular, we will emphasize the distinction between myeloablative and lymphoablative trials (en)
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Title
| - Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens
- Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens (en)
- Randomizovaná kontrolovaná studie autologní transplantace hematopoetických kmenových buněk pro autoimunitní onemocnění : evoluce od myeloablativních k lymfoablativním transplantačním režimům (cs)
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skos:prefLabel
| - Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens
- Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens (en)
- Randomizovaná kontrolovaná studie autologní transplantace hematopoetických kmenových buněk pro autoimunitní onemocnění : evoluce od myeloablativních k lymfoablativním transplantačním režimům (cs)
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skos:notation
| - RIV/00216208:11120/06:00001236!RIV09-MSM-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/06:00001236
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - systemic lupus erythematosus; bone marrow transplantation; dose immunosuppressive therapy; collagen vascular disease; phase I, II; rheumatoid arthritis; multiple sclerosis; radiation therapy; t cells; Crohns disease (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kozák, Tomáš
- Arnold, R.
- Snowden, J.
- Varga, J.
- Hiepe, F.
- Loh, Y.
- Slavin, S.
- Patel, D. D.
- Burt, R. K.
- Marmont, A.
- Oyama, Y.
- Statkute, L.
- Verda, L.
- Barr, W. G.
- Cohen, B. A.
- Collier, D.
- Craig, R. M.
- Fasses, A.
- Heslop, H.
- Hintzen, RQ.
- Krance, R.
- Myint, H.
- Rose, J. W.
- Schuening, F.
- Territo, M.
- Traynor, A.
- Voltarelli, J.
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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