About: A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis

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About: A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Dvojitě zaslepená randomizovaná multicentrická studie zaměřená na srovnání efektu lipidového komplexu Amfotericinu B a jeho kombinace s Mycograbem, protilátkou proti HS proteinu 90 u pacientů s invazivní kandidiazou. Mycograb byl dobře tolerován. Bylo prokázáno statisticky významné snížení mortality i hodnocených mikrobiologických parametrů (cs) A double-blind, randomized study was conducted to determine whether lipid-associated amphotericin B plus Mycograb (NeuTec)is superior to amphotericin B plus placebo in patients with culture-confirmed invasive candidiasis. Mycograbrab was well tolerated. Mycograb plus lipid-associated amphotericin B produced significant clinical and culture-confirmed improvement in outcome for patients with invasive candidiasis A double-blind, randomized study was conducted to determine whether lipid-associated amphotericin B plus Mycograb (NeuTec)is superior to amphotericin B plus placebo in patients with culture-confirmed invasive candidiasis. Mycograbrab was well tolerated. Mycograb plus lipid-associated amphotericin B produced significant clinical and culture-confirmed improvement in outcome for patients with invasive candidiasis (en)
Title	A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis (en) Randomizovaná, zaslepená, multicentrická studie se samostatně podaným lipidovým komplexem amfotericinu nebo v kombinaci s protilátkou inhibující HS 90 u pacientů s invazivní candidiazou (cs)
skos:prefLabel	A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis (en) Randomizovaná, zaslepená, multicentrická studie se samostatně podaným lipidovým komplexem amfotericinu nebo v kombinaci s protilátkou inhibující HS 90 u pacientů s invazivní candidiazou (cs)
skos:notation	RIV/00216208:11120/06:00000947!RIV09-MSM-11120___
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Pachl, J.
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	463787
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/06:00000947
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	invasive candidiasis; heat shock protein inhibitor; HS 90; heat shock protein antibody (en)
http://linked.open.../riv/klicoveSlovo	invasive candidiasis HS 90 heat shock protein antibody heat shock protein inhibitor
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[F3B5A9480DB9]
http://linked.open...i/riv/nazevZdroje	Clinical Infectious Diseases
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	42
http://linked.open...iv/tvurceVysledku	Svoboda, P. Pachl, Jan Drgona, L. Aoun, M. Burnie, J. Garbino, J. Jacobs, F. Malbrain, M. Masterson, G. Matthews, R. Spronk, P. Takala, J. Vandewoude, K. van der Hoven, B.
http://linked.open...ain/vavai/riv/wos	000237247400009
issn	1058-4838
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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