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| Description
| - A microdialysis technique was used to monitor changes in serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) and dopamine (DA) in the extracellular space of the parabrachial nucleus (PBN) of rats to estimate the contribution of these neurotransmitter systems to the acquisition of conditioned taste aversion (CTA). A ignificant (280%) enhancement of 5-HT was found immediately after saccharin drinking (CS). I.p. injection of unconditioned stimulus LiCl alone (after water drinking) also increased level of 5-HT (200%). However, when saccharin intake was followed by injection of LiCl (CS-US pairing), no change in 5-HT was observed. 5-HIAA and DA were unaffected by any of the above treatments. Thus in spite of elevation of 5-HT in PBN following saccharin consumption alone (CS) or LiCl administration alone (US) no changes in 5-HT occurred after pairing of both stimuli (CS-US). Our work demonstrates that participation of 5-HT in acquisition of CTA appears to be unlikely, and also DA appears not to be engag
- A microdialysis technique was used to monitor changes in serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) and dopamine (DA) in the extracellular space of the parabrachial nucleus (PBN) of rats to estimate the contribution of these neurotransmitter systems to the acquisition of conditioned taste aversion (CTA). A ignificant (280%) enhancement of 5-HT was found immediately after saccharin drinking (CS). I.p. injection of unconditioned stimulus LiCl alone (after water drinking) also increased level of 5-HT (200%). However, when saccharin intake was followed by injection of LiCl (CS-US pairing), no change in 5-HT was observed. 5-HIAA and DA were unaffected by any of the above treatments. Thus in spite of elevation of 5-HT in PBN following saccharin consumption alone (CS) or LiCl administration alone (US) no changes in 5-HT occurred after pairing of both stimuli (CS-US). Our work demonstrates that participation of 5-HT in acquisition of CTA appears to be unlikely, and also DA appears not to be engag (en)
- Pro sledování změn serotoninu (5-HT), 5-hydroxyindolacetátové kyseliny (5-HIAA) a dopaminu (DA) v extracelulárním prostoru ncl. parabrachialis (PBN) u laboratorního potkana byla použita mikrodialyzační technika pro zjištění přínosu tohoto neuropřenašečového systému pro akvizici podmíněné chuťové averze (CTA). Významný nárůst (208%) 5-HT byl zjištěn okamžitě po vypití sacharinu (CS). I.p. injekce nepodmíněného stimulu LiCl samotného (po vypití vody) také vedla ke zvýšení hladiny 5-HT (200%). Nicméně, když byl příjem sacharinu následován injekcí LiCl (CS-US párování), nebyla u 5-HT pozorována žádná změna. 5-HIAA a DA nebyly ovlivněny žádnými z výše zmíněných procedur. Tedy, navzory nárůstu 5-HT v PBN následující samotné vypití sacharinu (CS) nebo samotného podání LiCl (US) nebyly pozorovány žádné změny v 5-HT po párování obou podnětů (CS-US). Naše práce demonstruje, že účast 5-HT v akvizici CTA se zdá být nepravděpodobná a také že DA se zřejmě do akvizice vůbec nezapojuje. Na úrovni PBN se 5-HT účastní (cs)
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| Title
| - Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning
- Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning (en)
- Serotonin a dopamin v ncl. parabrachialis u laboratorního potkana během podmíněné chuťové averze (cs)
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| skos:prefLabel
| - Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning
- Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning (en)
- Serotonin a dopamin v ncl. parabrachialis u laboratorního potkana během podmíněné chuťové averze (cs)
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| skos:notation
| - RIV/00216208:11120/06:00000147!RIV07-MSM-11120___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(1M0517), Z(AV0Z5011922)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/06:00000147
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Taste aversion; Microdialysis; Serotonin; Dopamine; Parabrachial nucleus; Rat (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Behavioural Brain Research
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Zach, Petr
- Valeš, K.
- Křivánek, J.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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