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rdf:type
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Description
| - NMDA receptory jsou široce rozšířené, ligandy otevírané a napěťově závislé iontové kanály, citlivé současně na L-glutamát a glycin.
- NMDA receptory jsou široce rozšířené, ligandy otevírané a napěťově závislé iontové kanály, citlivé současně na L-glutamát a glycin. (cs)
- NMDA receptors are widely distributed, rapidly responding ligand-gated and voltage-dependent cationic channels sensitive to L-glutamate and glycine. The NMDA receptors are essential for the normal function of the excitatory glutamatergic neurotransmission. The receptor/channel complexes are highly permeable to Ca2+ and are subject to regulation by a variety of factors. Usually present as tetramers of protein subunits, NMDA receptors are formed by NR1, NR2 and/or NR3 subunits; however, all functional complexes must include NR1 subunits. The presence of NR2 and NR3 subunits and/or the nature of their spice variants may influence a range of NMDA receptor characteristics such as binding affinities for glutamate and glycine. Altered function of NMDA receptors has been linked to the etilogy of mental disease, particularly as a part of the %22glutmatergic hypothesis of schizophrenia%22. The functional changes in NMDA receptors could result from genetically determined variations in individual protein s (en)
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Title
| - Stavba a funkce NMDA receptoru u schizofrenie: od animálních modelů k pacientovi
- Stavba a funkce NMDA receptoru u schizofrenie: od animálních modelů k pacientovi (cs)
- Composition and function of NMDA receptor in schizophrenia: from animal models to a patient (en)
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skos:prefLabel
| - Stavba a funkce NMDA receptoru u schizofrenie: od animálních modelů k pacientovi
- Stavba a funkce NMDA receptoru u schizofrenie: od animálních modelů k pacientovi (cs)
- Composition and function of NMDA receptor in schizophrenia: from animal models to a patient (en)
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skos:notation
| - RIV/00216208:11120/06:00000079!RIV07-MSM-11120___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0517), P(NF7626), S, Z(MZ0PCP2005)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/06:00000079
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - glutamate; glycine; D-serine; NMDA receptor; NR1/NR2/NR3 subunits; animal model; schizophrenia (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Höschl, Cyril
- Šťastný, František
- Vrajová, Monika
- Tejkalová, H.
- Peková, S.
- Mareš, V.
- Balcar, V. J.
- Kozmiková, I.
- Jirásková, J.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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