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| Description
| - Intracellular parasite Toxoplasma gondii (TG) is considered to be an infectious agent, which plays a role in the aetiology and pathogenesis of some cases of shizophrenia. TG infection-related cognitive dysfunction is considered as an element of vulnerability for the development of some schizophrenia subtypes. The hypothesis that links TG infection and schizophrenia is supported above all by these findings: a) a statistically significant increase of antibody titres to TG in first-episode schizophrenia patients, b) a positive correlation of the antibodies to TG and psychopathology scores in first-episode schizophrenia, c) an increased level of cognitive abnormalities in schizophrenia patients with serologic evidence of TG infection compared to the patients without signs of TG infection, and d) cognitive and personality changes in TG infected non-##schizophrenic subjects and behavioural changes in animal models. The objectives of the CNS project are to investigate TG infected and non-infected subgroups o
- Intracellular parasite Toxoplasma gondii (TG) is considered to be an infectious agent, which plays a role in the aetiology and pathogenesis of some cases of shizophrenia. TG infection-related cognitive dysfunction is considered as an element of vulnerability for the development of some schizophrenia subtypes. The hypothesis that links TG infection and schizophrenia is supported above all by these findings: a) a statistically significant increase of antibody titres to TG in first-episode schizophrenia patients, b) a positive correlation of the antibodies to TG and psychopathology scores in first-episode schizophrenia, c) an increased level of cognitive abnormalities in schizophrenia patients with serologic evidence of TG infection compared to the patients without signs of TG infection, and d) cognitive and personality changes in TG infected non-##schizophrenic subjects and behavioural changes in animal models. The objectives of the CNS project are to investigate TG infected and non-infected subgroups o (en)
- Intracelulární parazit Toxoplasma gondii (TG) se řadí mezi potenciální infekční agens, která mohou hrát roli v etiologii a patogenezi některých schizofrenních onemocnění. Kognitivní dysfunkci vázanou na infekci TG lze pokládat za faktor vulnerability pro vznik některých podtypů schizofrenie. Hypotézu o souvislosti mezi TG infekcí a schizofrenií podporují především tyto nálezy: a) statisticky významně zvýšené titry protilátek proti TG u pacientů s první epizodou schizofrenie, b) pozitivní korelace mezi průkazem TG protilátek a skóry psychopatologie u prvních epizod schizofrenie, c) zvýšené kognitivní odchylky u schizofrenních nemocných se sérologickým průkazem TG infekce oproti pacientům bez známek TG infekce, d) kognitivní a osobnostní změny u neschizofrenních osob infikovaných TG a behaviorální změny na zvířecích modelech. Cílem CNS projektu je vyšetřit TG infikovanou a neinfikovanou podskupinu schizofrenních pacientů denního stacionáře s ohledem na: 1) odlišnou závažnost jejich symptomů a kognitivní (cs)
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| Title
| - Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates
- Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates (en)
- Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates (cs)
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| skos:prefLabel
| - Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates
- Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates (en)
- Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates (cs)
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| skos:notation
| - RIV/00216208:11120/06:00000019!RIV07-MSM-11120___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/06:00000019
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - schizophrenia; Toxoplasma gondii; psychopathology; cognitive dysfunction; first-episode schizophrenia; primary and secondary prevention in schizophrenia (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Čermák, Jan
- Preiss, M.
- Rodriguez, M.
- Motlová, Lucie
- Dragomirecká, E.
- Holub, D.
- Kaňková, Š.
- Nechutná, R.
- Ungrmanová, M.
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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