About: Clinical correlations of potential activity markers in systemic sclerosis

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The objectives of the project were the following: (1) to establish a group of patients with a confirmed diagnosis of systemic sclerosis (Ssc), (2) to perform a detailed entrance examination of each patient, (3) to determine concentrations of potential activity markers, and (4) to make a comprehensive examination of each patient I year after inclusion into the study. A total of 49 patients were examined, 36 with a limited form of SSc, 9 with diffuse SSc, and 4 with other forms of SSc. We determined plasma or serum levels of the N-terminal propeptide of procollagen type III (NPIIIP), interleukin-6 (IL-6), soluble receptor for interleukin-2 (sIL-2r), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular adhesion molecule-1 (sVCAM-1), von Willebrand factor antigen (vWFAg), and big endothelin-1 (BET-1) using commercial kits, and urinary excretion of pyridinoline (PYR) and deoxypyridinoline (D-PYR) using high-performance liquid chromatography. Correlations of these markers with selected clin The objectives of the project were the following: (1) to establish a group of patients with a confirmed diagnosis of systemic sclerosis (Ssc), (2) to perform a detailed entrance examination of each patient, (3) to determine concentrations of potential activity markers, and (4) to make a comprehensive examination of each patient I year after inclusion into the study. A total of 49 patients were examined, 36 with a limited form of SSc, 9 with diffuse SSc, and 4 with other forms of SSc. We determined plasma or serum levels of the N-terminal propeptide of procollagen type III (NPIIIP), interleukin-6 (IL-6), soluble receptor for interleukin-2 (sIL-2r), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular adhesion molecule-1 (sVCAM-1), von Willebrand factor antigen (vWFAg), and big endothelin-1 (BET-1) using commercial kits, and urinary excretion of pyridinoline (PYR) and deoxypyridinoline (D-PYR) using high-performance liquid chromatography. Correlations of these markers with selected clin (en)
Title	Clinical correlations of potential activity markers in systemic sclerosis Clinical correlations of potential activity markers in systemic sclerosis (en)
skos:prefLabel	Clinical correlations of potential activity markers in systemic sclerosis Clinical correlations of potential activity markers in systemic sclerosis (en)
skos:notation	RIV/00216208:11120/05:00002336!RIV11-MSM-11120___
http://linked.open...avai/riv/aktivita	N Z
http://linked.open...avai/riv/aktivity	N, Z(MZ00000023728)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Zatloukal, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	515509
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/05:00002336
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	systemic sclerosis; activity; collagen metabolism; adhesion molecules; interleukins (en)
http://linked.open.../riv/klicoveSlovo	interleukins activity adhesion molecules systemic sclerosis collagen metabolism
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[EE1DFF117913]
http://linked.open...i/riv/nazevZdroje	Annals of the New York Academy of Sciences
http://linked.open...in/vavai/riv/obor	FC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	1051
http://linked.open...iv/tvurceVysledku	Zatloukal, Petr
http://linked.open...ain/vavai/riv/wos	000233393100044
http://linked.open...n/vavai/riv/zamer	Výskyt, klinický průběh a léčba revmatických chorob - vytvoření celonárodního registru. Rozlišení forem osteoartrózy dle molekulárních změn v kloubu.
issn	0077-8923
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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