About: Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones

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About: Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones Goto Sponge NotDistinct Permalink

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rdfs:seeAlso	http://dx.doi.org/10.1099/jmm.0.45716-0
Description	The purpose of the present study was to investigate the diversity of the genes encoding aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan-European clones of Acinetobacter baumannii. The study collection included 106 multidrug-resistant strains previously allocated to clone I (n = 56), clone 11 (n = 36) and clone III (n = 6) and a heterogeneous group of other strains (n = 8), using AFLP fingerprinting and ribotyping. The strains were from hospitals of the Czech Republic (n = 70; collected 1991-2001) and 12 other European countries (n = 36; 1982-1998). Using PCR, at least one of the following aminoglycoside-resistance genes was detected in 101 (95%) strains: aphA 1 (n = 76), aacC1 (n = 68), aac(A 1 (n = 68), aphA6 (n = 55), aadB (n = 31), aacC2 (n = 7) and aacA4 (n = 3). A combination of two to five different resistance genes was observed in 89 strains (84%), with a total of 12 different combinations. PCR mapping revealed that aacC1, aadA 1 and aacA4 were each as The purpose of the present study was to investigate the diversity of the genes encoding aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan-European clones of Acinetobacter baumannii. The study collection included 106 multidrug-resistant strains previously allocated to clone I (n = 56), clone 11 (n = 36) and clone III (n = 6) and a heterogeneous group of other strains (n = 8), using AFLP fingerprinting and ribotyping. The strains were from hospitals of the Czech Republic (n = 70; collected 1991-2001) and 12 other European countries (n = 36; 1982-1998). Using PCR, at least one of the following aminoglycoside-resistance genes was detected in 101 (95%) strains: aphA 1 (n = 76), aacC1 (n = 68), aac(A 1 (n = 68), aphA6 (n = 55), aadB (n = 31), aacC2 (n = 7) and aacA4 (n = 3). A combination of two to five different resistance genes was observed in 89 strains (84%), with a total of 12 different combinations. PCR mapping revealed that aacC1, aadA 1 and aacA4 were each as (en)
Title	Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones (en)
skos:prefLabel	Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones (en)
skos:notation	RIV/00216208:11120/04:00003836!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita	P V
http://linked.open...avai/riv/aktivity	P(GA310/01/1540), V
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Nemec, Alexandr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	560923
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/04:00003836
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Antibiotic-Resistance; Identification; Hospitals; PCR; Reveals; Regions; Spain (en)
http://linked.open.../riv/klicoveSlovo	Hospitals Regions Identification PCR Spain Antibiotic-Resistance Reveals
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[F050FFB037F0]
http://linked.open...i/riv/nazevZdroje	Journal of Medical Microbiology
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Evolution of multiresistance in Acinetobacter baumannii: the relationship betwen clonality and aminoglycoside resistance
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Nemec, Alexandr
http://linked.open...ain/vavai/riv/wos	000225893300010
issn	0022-2615
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1099/jmm.0.45716-0
http://localhost/t...ganizacniJednotka	11120

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