About: Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In the present study, we investigated markers of exposition in a cohort of 110 tire plant workers in relation to various polymorphisms in genes coding for biotransformation and DNA repair enzymes. The results from this study suggest the importance of evaluating markers of individual susceptibility, since they may modulate genotoxic effects induced by occupational exposure to xenobiotics. In the present study, we investigated markers of exposition in a cohort of 110 tire plant workers in relation to various polymorphisms in genes coding for biotransformation and DNA repair enzymes. The results from this study suggest the importance of evaluating markers of individual susceptibility, since they may modulate genotoxic effects induced by occupational exposure to xenobiotics. (en) V této práci jsme sledovali markery expozice skupiny 110 dělníků vyrábějících pneumatiky ve vztahu k polymorfismu genů kodujících biotransformační a DNA reparační enzymy. Výsledky naznačují důležitost vyhodnocování markerů individuální citlivosti, protože mohou modulovat genotoxické efekty profesionální expozice xenobiotiky. (cs)
Title	Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant Markery individuální vnímavosti a rychlosti reparace DNA u pracovníků exponovaných xenobiotikům při výrobě pneumatik (cs) Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant (en)
skos:prefLabel	Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant Markery individuální vnímavosti a rychlosti reparace DNA u pracovníků exponovaných xenobiotikům při výrobě pneumatik (cs) Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant (en)
skos:notation	RIV/00216208:11120/04:00001208!RIV/2005/GA0/111205/N
http://linked.open.../vavai/riv/strany	283;292
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/01/0802), P(GA310/03/0437), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Vodička, Pavel Štětina, Rudolf
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	572324
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/04:00001208
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	workers; xenobiotics; plant (en)
http://linked.open.../riv/klicoveSlovo	xenobiotics workers plant
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[9AA7D0641FAB]
http://linked.open...i/riv/nazevZdroje	Environmental and Molecular Mutagenesis
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	16 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanisms of genotoxic effects of chemical carcinogen 1,3butadien: adaptive response and individual susceptibility New aspects in understanding styrene genotoxicity: the role of DNA repair,new reactive metabolites and secondary oxidative stress
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	44
http://linked.open...iv/tvurceVysledku	Vodička, Pavel Štětina, Rudolf
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy
issn	0893-6692
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

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