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Description
  • VMK hrají klíčovou roli při vzniku inzulínové rezistence. Dostupnost VMK je dána především jejich mobilizací ztukové tkáně. Jsou popisovány regulační mechanizmy lipolýzy tukové tkáně (hormonální, parakrinní a autokrinní signály) a možnosti ovlivnění těchto mechanizmů (energetický příjem , tělesné cvičení, trénink). (cs)
  • Plasma NEFA are an important energy substrate and, furthermore, play a key role in the induction of insulin resistance in the body. The availability of NEFA is determined predominantly by their mobilization from adipose tissue triacylglycerol stores by the process of lipolysis. Adipose tissue lipolysis in man is regulated by a number of hormonal and paracrine and/or autocrine signals. The main hormonal signals may be represented by catecholamines, insulin, growth hormone, natriuretic peptides and some adipocytokines. The absolute levels and relative importance and contribution of these signals vary in different physiological situations, with diet and physical exercise being the main physiological variables that affect the hormonal signalling. Thus, modulations in hormonal signals induce an increase in NEFA mobilization in the post-absorptive state and during an acute bout of exercise, and suppress NEFA mobilization in the postprandial state.
  • Plasma NEFA are an important energy substrate and, furthermore, play a key role in the induction of insulin resistance in the body. The availability of NEFA is determined predominantly by their mobilization from adipose tissue triacylglycerol stores by the process of lipolysis. Adipose tissue lipolysis in man is regulated by a number of hormonal and paracrine and/or autocrine signals. The main hormonal signals may be represented by catecholamines, insulin, growth hormone, natriuretic peptides and some adipocytokines. The absolute levels and relative importance and contribution of these signals vary in different physiological situations, with diet and physical exercise being the main physiological variables that affect the hormonal signalling. Thus, modulations in hormonal signals induce an increase in NEFA mobilization in the post-absorptive state and during an acute bout of exercise, and suppress NEFA mobilization in the postprandial state. (en)
Title
  • Physiological regulation of NEFA availability: lipolysis pathway
  • Physiological regulation of NEFA availability: lipolysis pathway (en)
  • Fyziologická regulace dostupnosti VMK: lipolytická cesta (cs)
skos:prefLabel
  • Physiological regulation of NEFA availability: lipolysis pathway
  • Physiological regulation of NEFA availability: lipolysis pathway (en)
  • Fyziologická regulace dostupnosti VMK: lipolytická cesta (cs)
skos:notation
  • RIV/00216208:11120/04:00001135!RIV/2005/MZ0/111205/N
http://linked.open.../vavai/riv/strany
  • 369;374
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NB6836)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 579532
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/04:00001135
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Physiological;regulation;availability;lipolysis;pathway (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [7D63860669D7]
http://linked.open...i/riv/nazevZdroje
  • Nutrition Society. Proceedings
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 63
http://linked.open...iv/tvurceVysledku
  • Štich, Vladimír
issn
  • 0029-6651
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http://localhost/t...ganizacniJednotka
  • 11120
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