About: Long-term changes of activity of cortical neurons after status epilepticus induced at early developmental stages in rats     Goto   Sponge   NotDistinct   Permalink

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Description
  • Spontaneous activity of cortical neurons was studied under urethane anesthesia in adult rats 3 months after convulsive status epilepticus induced by lithium-pilocarpine administration at the age of 12 (SE12 group) or 25 (SE25 group) days. Whereas random firing neurons dominated in control animals (61 out of 98 cells), SE25 animals exhibited a significant increase in the incidence of bursting cells (38 out of 59 units). Similar change in SE12 animals did not reach the level of statistical significance. Status epilepticus at an early developmental stage may result in a long-lasting change in functions of surviving cortical neurons
  • Spontaneous activity of cortical neurons was studied under urethane anesthesia in adult rats 3 months after convulsive status epilepticus induced by lithium-pilocarpine administration at the age of 12 (SE12 group) or 25 (SE25 group) days. Whereas random firing neurons dominated in control animals (61 out of 98 cells), SE25 animals exhibited a significant increase in the incidence of bursting cells (38 out of 59 units). Similar change in SE12 animals did not reach the level of statistical significance. Status epilepticus at an early developmental stage may result in a long-lasting change in functions of surviving cortical neurons (en)
Title
  • Long-term changes of activity of cortical neurons after status epilepticus induced at early developmental stages in rats
  • Long-term changes of activity of cortical neurons after status epilepticus induced at early developmental stages in rats (en)
skos:prefLabel
  • Long-term changes of activity of cortical neurons after status epilepticus induced at early developmental stages in rats
  • Long-term changes of activity of cortical neurons after status epilepticus induced at early developmental stages in rats (en)
skos:notation
  • RIV/00216208:11120/03:00003642!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA309/00/1643), P(GA309/03/0770), Z(AV0Z5011922), Z(MSM 111200005)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 613864
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/03:00003642
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Long-term; changes; activity; cortical; neurons; after; status; epilepticus; induced; early; developmental; stages; rats (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • IE - Irsko
http://linked.open...ontrolniKodProRIV
  • [957F0A20421D]
http://linked.open...i/riv/nazevZdroje
  • Neuroscience Letters
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 352
http://linked.open...iv/tvurceVysledku
  • Mareš, Pavel
  • Bernášková, Klára
  • Doczi, J.
http://linked.open...ain/vavai/riv/wos
  • 000186680400013
http://linked.open...n/vavai/riv/zamer
issn
  • 0304-3940
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.neulet.2003.08.043
http://localhost/t...ganizacniJednotka
  • 11120
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