About: Relevant animal model of human lymphoblastic leukaemia/lymphoma - Spontaneous T-cell lymphomas in an inbred sprague-dawley rat strain (SD/Cub)

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Relevant animal model of human lymphoblastic leukaemia/lymphoma - Spontaneous T-cell lymphomas in an inbred sprague-dawley rat strain (SD/Cub) Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	More than a decade of experimental work in an inbred subline of Sprague-Dawley rats having high incidence of spontaneous T-cell lymphoma/leukaemia is reviewed. Longitudinal follow-up of biological characteristics (growth, survival, haematology) of both multiple cases of primary disease and s.c. passaged lymphomas as well as comparative immunophenotypic and karyotypic studies are concluded. In these T-cell lymphomas (mostly CD4 positive), arising on the same genetic background of the inbred SD strain, the aberrations involving chromosome 11 have been recognized as a typical non-random cytogenetic marker. This unique rat model of lymphoblastic lymphomas/leukaemias, relevant to human pathology, seems to be very suitable for testing different anticancer therapeutic strategies, as it is documented by results of a number of various protocols conducted in our laboratory. More than a decade of experimental work in an inbred subline of Sprague-Dawley rats having high incidence of spontaneous T-cell lymphoma/leukaemia is reviewed. Longitudinal follow-up of biological characteristics (growth, survival, haematology) of both multiple cases of primary disease and s.c. passaged lymphomas as well as comparative immunophenotypic and karyotypic studies are concluded. In these T-cell lymphomas (mostly CD4 positive), arising on the same genetic background of the inbred SD strain, the aberrations involving chromosome 11 have been recognized as a typical non-random cytogenetic marker. This unique rat model of lymphoblastic lymphomas/leukaemias, relevant to human pathology, seems to be very suitable for testing different anticancer therapeutic strategies, as it is documented by results of a number of various protocols conducted in our laboratory. (en)
Title	Relevant animal model of human lymphoblastic leukaemia/lymphoma - Spontaneous T-cell lymphomas in an inbred sprague-dawley rat strain (SD/Cub) Relevant animal model of human lymphoblastic leukaemia/lymphoma - Spontaneous T-cell lymphomas in an inbred sprague-dawley rat strain (SD/Cub) (en)
skos:prefLabel	Relevant animal model of human lymphoblastic leukaemia/lymphoma - Spontaneous T-cell lymphomas in an inbred sprague-dawley rat strain (SD/Cub) Relevant animal model of human lymphoblastic leukaemia/lymphoma - Spontaneous T-cell lymphomas in an inbred sprague-dawley rat strain (SD/Cub) (en)
skos:notation	RIV/00216208:11120/02:00003695!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita	V Z
http://linked.open...avai/riv/aktivity	V, Z(AV0Z5039906), Z(MSM 111100004)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Mandys, Václav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	662042
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/02:00003695
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	T-cell; lymphoma; leukaemia; rat model; immunophenotype; cytogenetics; cell cycle; immunochemistry; experimental therapy (en)
http://linked.open.../riv/klicoveSlovo	experimental therapy T-cell immunochemistry rat model lymphoma leukaemia immunophenotype cell cycle cytogenetics
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[B75583D6E966]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	48
http://linked.open...iv/tvurceVysledku	Mandys, Václav Otová, B.
http://linked.open...ain/vavai/riv/wos	000180060500001
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111100004
issn	0015-5500
number of pages	13 (xsd:int)
http://localhost/t...ganizacniJednotka	11120

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 77 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software