About: Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women

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About: Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1210/jc.87.3.1274
Description	Previous investigations have shown that alpha2-adrenoceptor (alpha2-AR) stimulation blunts lipid mobilization during physiological activation of the sympathetic nervous system promoted by exercise in se abdominal adipose tissue (SCAAT) in obese men. To investigate the effect of a low calorie diet (LCD) on the alpha2-adrenergic responsiveness and on the expression of alpha2-AR and beta2-adrenoceptor (beta2-AR) in SCAAT, 11 obese women (weight: 99.1 +/- 4.6 kg; body mass index: 34.3 +/- 1.1 kg/m(2)) received a 12-wk diet providing 500 kcal/d less than their usual diet. The exercise-induced alpha2-adrenergic antilipolytic effect was investigated in SCAAT before and at the end of LCD. Changes in extracellular glycerol concentration and local blood flow were measured in SCAAT during a 45-min exercise bout (50% of heart rate reserve) using a control microdialysis probe and a probe supplemented with the alpha2-AR antagonist phentolamine. SCAAT biopsies were performed for determination of mRNA levels using RT Previous investigations have shown that alpha2-adrenoceptor (alpha2-AR) stimulation blunts lipid mobilization during physiological activation of the sympathetic nervous system promoted by exercise in se abdominal adipose tissue (SCAAT) in obese men. To investigate the effect of a low calorie diet (LCD) on the alpha2-adrenergic responsiveness and on the expression of alpha2-AR and beta2-adrenoceptor (beta2-AR) in SCAAT, 11 obese women (weight: 99.1 +/- 4.6 kg; body mass index: 34.3 +/- 1.1 kg/m(2)) received a 12-wk diet providing 500 kcal/d less than their usual diet. The exercise-induced alpha2-adrenergic antilipolytic effect was investigated in SCAAT before and at the end of LCD. Changes in extracellular glycerol concentration and local blood flow were measured in SCAAT during a 45-min exercise bout (50% of heart rate reserve) using a control microdialysis probe and a probe supplemented with the alpha2-AR antagonist phentolamine. SCAAT biopsies were performed for determination of mRNA levels using RT (en)
Title	Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women (en)
skos:prefLabel	Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women (en)
skos:notation	RIV/00216208:11120/02:00002995!RIV12-GA0-11120___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA303/00/0649)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hejnová, Jindřiška Suljkovičová, Hana Štich, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	648214
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/02:00002995
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Blood-Flow; Alpha(2)-Adrenergic Receptors; Adrenergic Regulation; Lipolytic Response; Weight-Loss; Glycerol; Microdialysis; Humans; Mobilization; Epinephrine (en)
http://linked.open.../riv/klicoveSlovo	Microdialysis Glycerol Mobilization Adrenergic Regulation Alpha(2)-Adrenergic Receptors Lipolytic Response Humans Epinephrine Blood-Flow Weight-Loss
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[F67603A15A6C]
http://linked.open...i/riv/nazevZdroje	Journal of Clinical Endocrinology and Metabolism
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Effect of high-fat diet on metabolism of adipose tissue
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	87
http://linked.open...iv/tvurceVysledku	Štich, Vladimír Hejnová, Jindřiška Suljkovičová, Hana
http://linked.open...ain/vavai/riv/wos	000174620600053
issn	0021-972X
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1210/jc.87.3.1274
http://localhost/t...ganizacniJednotka	11120

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