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Description
| - A clinical study was performed to determine the effect of the sequential combined estrogen-progestogen drug Klimonorm (R) on changes in bone density and bone metabolism in 74 nonmenopausal women who underwent abdominal hysterectomy with bilateral adnexectomy. The women started therapy with Klimonorm (R) 3-5 years after surgically induced menopause and it was continued for a period of 1-2 years. The following determinations were made: bone mineral density (BMD), T-score, Z-score, body mass index (BMI), plasma levels of 17 beta -estradiol, estrone, osteocalcin, ionized calcium (Ca2+), ionized phosphate (PO42-), alkaline phosphatase, hemoglobin and hematocrit and urine concentrations of hydroxyproline, Ca2+ and PO42-. The BMD, T-score and Z-score were significantly reduced in women with surgical menopause. Therapy with Klimonorm (R) significantly improved these indices. Plasma levels of 17 beta -estradiol and estrone increased considerably during the therapy. The plasma concentration of alkaline phosphat
- A clinical study was performed to determine the effect of the sequential combined estrogen-progestogen drug Klimonorm (R) on changes in bone density and bone metabolism in 74 nonmenopausal women who underwent abdominal hysterectomy with bilateral adnexectomy. The women started therapy with Klimonorm (R) 3-5 years after surgically induced menopause and it was continued for a period of 1-2 years. The following determinations were made: bone mineral density (BMD), T-score, Z-score, body mass index (BMI), plasma levels of 17 beta -estradiol, estrone, osteocalcin, ionized calcium (Ca2+), ionized phosphate (PO42-), alkaline phosphatase, hemoglobin and hematocrit and urine concentrations of hydroxyproline, Ca2+ and PO42-. The BMD, T-score and Z-score were significantly reduced in women with surgical menopause. Therapy with Klimonorm (R) significantly improved these indices. Plasma levels of 17 beta -estradiol and estrone increased considerably during the therapy. The plasma concentration of alkaline phosphat (en)
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Title
| - Changes in bone density and bone metabolism in women with surgically induced menopause treated with a hormone replacement drug containing estradiol valerate and levonorgestrel
- Changes in bone density and bone metabolism in women with surgically induced menopause treated with a hormone replacement drug containing estradiol valerate and levonorgestrel (en)
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skos:prefLabel
| - Changes in bone density and bone metabolism in women with surgically induced menopause treated with a hormone replacement drug containing estradiol valerate and levonorgestrel
- Changes in bone density and bone metabolism in women with surgically induced menopause treated with a hormone replacement drug containing estradiol valerate and levonorgestrel (en)
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skos:notation
| - RIV/00216208:11120/01:00003654!RIV12-MSM-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/01:00003654
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Biochemical Markers; Therapy; Estrogen; Prevention; Osteoporosis; Fractures; Turnover (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - ES - Španělské království
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Živný, J.
- Jeníček, Jaroslav
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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