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  • Immune function parameters represent important tools for the evaluation of individual health risk in workers occupationally exposed to immunotoxic industrial chemicals. In vitro lymphocyte proliferation assays were used for biomonitoring of groups of workers occupationally exposed to polycyclic aromatic hydrocarbons in a rubber factory, and to styrene in the plastic lamination plant. Adhesion molecules were measured by Row cytometry in peripheral blood of workers exposed to styrene. In our studies in vitro lymphocyte proliferation assays were sensitive indicators of immunotoxic effects of industrial chemicals. Workers exposed to polycyclic aromatic hydrocarbons in rubber manufacture displayed enhanced lymphocyte proliferation. Workers occupationally exposed to styrene had suppressed lymphocyte mitogen proliferation response. Styrene exposure appeared to activate the immune system and alter leukocytes adherence.
  • Immune function parameters represent important tools for the evaluation of individual health risk in workers occupationally exposed to immunotoxic industrial chemicals. In vitro lymphocyte proliferation assays were used for biomonitoring of groups of workers occupationally exposed to polycyclic aromatic hydrocarbons in a rubber factory, and to styrene in the plastic lamination plant. Adhesion molecules were measured by Row cytometry in peripheral blood of workers exposed to styrene. In our studies in vitro lymphocyte proliferation assays were sensitive indicators of immunotoxic effects of industrial chemicals. Workers exposed to polycyclic aromatic hydrocarbons in rubber manufacture displayed enhanced lymphocyte proliferation. Workers occupationally exposed to styrene had suppressed lymphocyte mitogen proliferation response. Styrene exposure appeared to activate the immune system and alter leukocytes adherence. (en)
Title
  • Immune markers in biological monitoring of occupationally exposed workers
  • Immune markers in biological monitoring of occupationally exposed workers (en)
skos:prefLabel
  • Immune markers in biological monitoring of occupationally exposed workers
  • Immune markers in biological monitoring of occupationally exposed workers (en)
skos:notation
  • RIV/00216208:11120/01:00003593!RIV12-GA0-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA313/99/1460), Z(AV0Z5039906)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 682397
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/01:00003593
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • biological monitoring; styrene; polycyclic aromatic hydrocarbons; immune markers; cellular immunity; adhesion molecules; rubber (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SK - Slovenská republika
http://linked.open...ontrolniKodProRIV
  • [58C5BA055E26]
http://linked.open...i/riv/nazevZdroje
  • Biológia
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 56
http://linked.open...iv/tvurceVysledku
  • Vodička, Pavel
  • Kuricová, Miroslava
http://linked.open...ain/vavai/riv/wos
  • 000169340900011
http://linked.open...n/vavai/riv/zamer
issn
  • 0006-3088
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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