About: A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue     Goto   Sponge   NotDistinct   Permalink

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Description
  • This study was designed to assess whether physiological activation of the sympathetic nervous system induced by exercise changes adipose tissue responsiveness to catecholamines in humans. Lipid mobilization in abdominal subcutaneous adipose tissue was studied with the use of a microdialysis method in 11 nontrained men (age: 22.3 +/- 1.5 yr; body mass index: 23.0 +/- 1.6). Adipose tissue adrenergic sensitivity was explored with norepinephrine, dobutamine (beta (1)-agonist), or terbutaline (beta (2)-agonist) perfused during 30 min through probes before and after 60-min exercise (50% of the maximal aerobic power). The increase in extracellular glycerol concentration during infusion was significantly lower after the exercise when compared with the increase observed before the exercise (P < 0.05, P < 0.02, and P < 0.01, respectively, for norepinephrine, dobutamine, and terbutaline).
  • This study was designed to assess whether physiological activation of the sympathetic nervous system induced by exercise changes adipose tissue responsiveness to catecholamines in humans. Lipid mobilization in abdominal subcutaneous adipose tissue was studied with the use of a microdialysis method in 11 nontrained men (age: 22.3 +/- 1.5 yr; body mass index: 23.0 +/- 1.6). Adipose tissue adrenergic sensitivity was explored with norepinephrine, dobutamine (beta (1)-agonist), or terbutaline (beta (2)-agonist) perfused during 30 min through probes before and after 60-min exercise (50% of the maximal aerobic power). The increase in extracellular glycerol concentration during infusion was significantly lower after the exercise when compared with the increase observed before the exercise (P < 0.05, P < 0.02, and P < 0.01, respectively, for norepinephrine, dobutamine, and terbutaline). (en)
Title
  • A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue
  • A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue (en)
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  • A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue
  • A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue (en)
skos:notation
  • RIV/00216208:11120/01:00003135!RIV12-MZ0-11120___
http://linked.open...avai/riv/aktivita
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  • P(IZ3611)
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  • 1
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  • 672331
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  • RIV/00216208:11120/01:00003135
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  • lipolysis; catecholamines; dobutamine; terbutaline (en)
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  • US - Spojené státy americké
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  • [39D3D0E65DE2]
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  • American Journal of Physiology - Regulatory Integrative and Comparative Physiology
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 280
http://linked.open...iv/tvurceVysledku
  • Štich, Vladimír
  • Suljkovičová, Hana
http://linked.open...ain/vavai/riv/wos
  • 000165955400022
issn
  • 0363-6119
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  • 11120
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