About: Bromide kinetics and distribution in the rat: II. Distribution of bromide in the body

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1385/BTER:76:1:67
Description	The distribution of Br-82-bromide in 15 different organs and tissues of rats has been determined by high-resolution gamma-ray spectrometry and by the scintillation counting technique at different times after the application of Na Br-82, either by subcutaneous injection or by continuous administration in the drinking water. The amount of Br-82-bromide in the various tissues reached its largest uptake within a few hours, and the concentration ratio of Br-82 in the tissues to blood remained practically constant between 8 and 396 h after the applica tion. The whole stomach of rats was the only organ of those investigated that had a larger uptake of Br-82 than blood. Contrary to some previous findings, the concentration of radiobromide in the thyroid was found not to exceed that in the blood. A remarkably high concentration of Br-82 was found in the skin, which represented, because of its large mass, the most abundant depot of bromide in the body of rats. The distribution of Br-82-bromide in 15 different organs and tissues of rats has been determined by high-resolution gamma-ray spectrometry and by the scintillation counting technique at different times after the application of Na Br-82, either by subcutaneous injection or by continuous administration in the drinking water. The amount of Br-82-bromide in the various tissues reached its largest uptake within a few hours, and the concentration ratio of Br-82 in the tissues to blood remained practically constant between 8 and 396 h after the applica tion. The whole stomach of rats was the only organ of those investigated that had a larger uptake of Br-82 than blood. Contrary to some previous findings, the concentration of radiobromide in the thyroid was found not to exceed that in the blood. A remarkably high concentration of Br-82 was found in the skin, which represented, because of its large mass, the most abundant depot of bromide in the body of rats. (en)
Title	Bromide kinetics and distribution in the rat: II. Distribution of bromide in the body Bromide kinetics and distribution in the rat: II. Distribution of bromide in the body (en)
skos:prefLabel	Bromide kinetics and distribution in the rat: II. Distribution of bromide in the body Bromide kinetics and distribution in the rat: II. Distribution of bromide in the body (en)
skos:notation	RIV/00216208:11120/00:00003627!RIV12-MZ0-11120___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA7011813), P(NJ6109), Z(AV0Z4031919), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Lener, Jaroslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	705938
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/00:00003627
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Bromide; distribution; radionuclide 82-Br; rat (en)
http://linked.open.../riv/klicoveSlovo	Bromide distribution rat radionuclide 82-Br
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[D80F4A50CFD6]
http://linked.open...i/riv/nazevZdroje	Biological Trace Element Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Interference of bromide from the environment with iodine metabolism in the thyroid gland and other tissues The influence of an excess of bromine and/or iodine deficiency on the metabolism of thyroid hormones in tissues
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	76
http://linked.open...iv/tvurceVysledku	Pavelka, Stanislav Lener, Jaroslav
http://linked.open...n/vavai/riv/zamer	Vyvinutí nových metod analytické chemie pro potřeby společenské praxe Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0163-4984
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1385/BTER:76:1:67
http://localhost/t...ganizacniJednotka	11120

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