About: Solitary tuberculous brain lesions: 24 new cases and a review of the literature

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S0035378714007991
Description	A solitary tuberculous brain lesion (STBL) can be difficult to distinguish from a glioma, metastasis or other infectious disease, especially from a pyogenic brain abscess. We analyzed the clinical characteristics, diagnostic procedures and outcomes of 24 patients with STBL diagnosed in three centers from France, India and Mexico. We also reviewed 92 STBL cases previously reported in the literature. General symptoms were found in 54% of our patients, including enlarged lymph nodes in 20%. Cerebrospinal fluid was typically abnormal, with lymphocytic pleocytosis and a high protein level. The lung CT scan was abnormal in 56% of patients, showing lymphadenopathy or pachipleuritis. Brain MRI or CT was always abnormal, showing contrast-enhanced lesions. Typically, MRI abnormalities were hypointense on T1-weighted sequences, while T2-weighted sequences showed both a peripheral hypersignal and a central hyposignal. The diagnosis was documented microbiologically or supported histologically in 71% of cases. Clinical outcome was good in 83% of cases. A solitary tuberculous brain lesion (STBL) can be difficult to distinguish from a glioma, metastasis or other infectious disease, especially from a pyogenic brain abscess. We analyzed the clinical characteristics, diagnostic procedures and outcomes of 24 patients with STBL diagnosed in three centers from France, India and Mexico. We also reviewed 92 STBL cases previously reported in the literature. General symptoms were found in 54% of our patients, including enlarged lymph nodes in 20%. Cerebrospinal fluid was typically abnormal, with lymphocytic pleocytosis and a high protein level. The lung CT scan was abnormal in 56% of patients, showing lymphadenopathy or pachipleuritis. Brain MRI or CT was always abnormal, showing contrast-enhanced lesions. Typically, MRI abnormalities were hypointense on T1-weighted sequences, while T2-weighted sequences showed both a peripheral hypersignal and a central hyposignal. The diagnosis was documented microbiologically or supported histologically in 71% of cases. Clinical outcome was good in 83% of cases. (en)
Title	Solitary tuberculous brain lesions: 24 new cases and a review of the literature Solitary tuberculous brain lesions: 24 new cases and a review of the literature (en)
skos:prefLabel	Solitary tuberculous brain lesions: 24 new cases and a review of the literature Solitary tuberculous brain lesions: 24 new cases and a review of the literature (en)
skos:notation	RIV/00216208:11110/14:10292332!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	6-7
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Bonnet, Cecilia
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	45902
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/14:10292332
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Magnetic resonance imaging; Cerebral biopsy; Brain abscess; Glioma; Brain tuberculosis; Tuberculoma (en)
http://linked.open.../riv/klicoveSlovo	Glioma Magnetic resonance imaging Brain abscess Brain tuberculosis Cerebral biopsy Tuberculoma
http://linked.open...odStatuVydavatele	FR - Francouzská republika
http://linked.open...ontrolniKodProRIV	[A4FB469FE0E5]
http://linked.open...i/riv/nazevZdroje	Revue Neurologique
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	15 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	170
http://linked.open...iv/tvurceVysledku	Bonnet, Cecilia Roze, E. Behari, S. Cardenas, G. Caumes, E. Heinzmann, A. Jose Luis, S. Hernandez Karantoni, E. Lacrois, D. Mohamed, N. Idris Mokhtari, K. Psimaras, D. Sonmez, G. Tag, E. Sokrab Tungaria, A.
http://linked.open...ain/vavai/riv/wos	000338756500008
issn	0035-3787
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.neurol.2013.12.008
http://localhost/t...ganizacniJednotka	11110

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