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rdf:type
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rdfs:seeAlso
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Description
| - The common 2652 6N del variant in the CASP8 promoter (rs3834129) has been described as a putative low-penetrance risk factor for different cancer types. In particular, some studies suggested that the deleted allele (del) was inversely associated with CRC risk while other analyses failed to confirm this. Hence, to better understand the role of this variant in the risk of developing CRC, we performed a multi-centric case-control study. In the study, the variant 2652 6N del was genotyped in a total of 6,733 CRC cases and 7,576 controls recruited by six different centers located in Spain, Italy, USA, England, Czech Republic and the Netherlands collaborating to the international consortium COGENT (COlorectal cancer GENeTics).
- The common 2652 6N del variant in the CASP8 promoter (rs3834129) has been described as a putative low-penetrance risk factor for different cancer types. In particular, some studies suggested that the deleted allele (del) was inversely associated with CRC risk while other analyses failed to confirm this. Hence, to better understand the role of this variant in the risk of developing CRC, we performed a multi-centric case-control study. In the study, the variant 2652 6N del was genotyped in a total of 6,733 CRC cases and 7,576 controls recruited by six different centers located in Spain, Italy, USA, England, Czech Republic and the Netherlands collaborating to the international consortium COGENT (COlorectal cancer GENeTics). (en)
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Title
| - Association between CASP8 -652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study
- Association between CASP8 -652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study (en)
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skos:prefLabel
| - Association between CASP8 -652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study
- Association between CASP8 -652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study (en)
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skos:notation
| - RIV/00216208:11110/14:10284323!RIV15-MSM-11110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(GAP304/10/1286), P(GAP304/12/1585)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11110/14:10284323
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - multicentric approach; case-control study; rs3834129; CASP8 -652 6N del polymorphism; association study; CRC susceptibility; CRC risk (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Naccarati, Alessio
- Pardini, Barbara
- Vodička, Pavel
- Vodičková, Ludmila
- Li, Li
- Vymetálková, Veronika
- Carracedo, Angel
- Castells, Antoni
- Castellvi-Bel, Sergi
- Nici, Carmela
- Peterlongo, Paolo
- Radice, Paolo
- Ruiz-Ponte, Clara
- Tomlinson, Ian
- Veneroni, Silvia
- Bianchi, Tiziana
- Bujanda, Luis
- Daidone, Maria Grazia
- Howarth, Kimberley
- Jones, Angela
- Maiorana, Maria Valeria
- Morreau, Hans
- Pizzamiglio, Sara
- Ravagnani, Fernando
- Van Wezel, Tom
- Verderio, Paolo
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1371/journal.pone.0085538
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http://localhost/t...ganizacniJednotka
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