About: Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis

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About: Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://ard.bmj.com/content/73/10/1898
Description	Identification of parameters for early diagnosis and treatment response would be beneficial for patients with early rheumatoid arthritis (ERA) to prevent ongoing joint damage. MiRNAs have features of potential biomarkers and an altered expression of miRNAs was shown in established RA. The aim of our study was to analyze RA-associated miRNAs in sera of patients with ERA to find markers of early disease, clinical activity or predictors of disease outcome We have described a differential expression of circulating miR-146a, miR-155 and miR-16 in sera from ERA patients may characterize an early stage of the disease. We suggest miR-223 as a marker of disease activity and miR-16 and miR-223 as possible predictors for disease outcome in ERA. Identification of parameters for early diagnosis and treatment response would be beneficial for patients with early rheumatoid arthritis (ERA) to prevent ongoing joint damage. MiRNAs have features of potential biomarkers and an altered expression of miRNAs was shown in established RA. The aim of our study was to analyze RA-associated miRNAs in sera of patients with ERA to find markers of early disease, clinical activity or predictors of disease outcome We have described a differential expression of circulating miR-146a, miR-155 and miR-16 in sera from ERA patients may characterize an early stage of the disease. We suggest miR-223 as a marker of disease activity and miR-16 and miR-223 as possible predictors for disease outcome in ERA. (en)
Title	Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis (en)
skos:prefLabel	Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis (en)
skos:notation	RIV/00216208:11110/14:10283585!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Pavelka, Karel Šenolt, Ladislav Mann, Heřman Vencovský, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	4351
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/14:10283585
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	rheumatoid arthritis; biomarker; miRNA (en)
http://linked.open.../riv/klicoveSlovo	miRNA rheumatoid arthritis biomarker
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[5B11ABCEE2B5]
http://linked.open...i/riv/nazevZdroje	Annals of the Rheumatic Diseases
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	16 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	73
http://linked.open...iv/tvurceVysledku	Mann, Heřman Pavelka, Karel Vencovský, Jiří Šenolt, Ladislav Filer, Andrew Raza, Karim Aradi, Borbala Buckley, Christopher D. Filkova, Maria Gay, Renate E. Gay, Steffen Juengel, Astrid Michel, Beat A. Ospelt, Caroline Snow, Martyn Vettori, Serena
http://linked.open...ain/vavai/riv/wos	000341789500028
issn	0003-4967
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1136/annrheumdis-2012-202815
http://localhost/t...ganizacniJednotka	11110

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