About: Studying dynamic events in the developing myocardium

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Studying dynamic events in the developing myocardium Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.pbiomolbio.2014.06.002
Description	Differentiation and conduction properties of the cardiomyocytes are critically dependent on physical conditioning both in vitro and in vivo. Historically, various techniques were introduced to study dynamic events such as electrical currents and changes in ionic concentrations in live cells, multicellular preparations, or entire hearts. Here we review this technological progress demonstrating how each improvement in spatial or temporal resolution provided answers to old and provoked new questions. We further demonstrate how high-speed optical mapping of voltage and calcium can uncover pacemaking potential within the outflow tract myocardium, providing a developmental explanation of ectopic beats originating from this region in the clinical settings. Differentiation and conduction properties of the cardiomyocytes are critically dependent on physical conditioning both in vitro and in vivo. Historically, various techniques were introduced to study dynamic events such as electrical currents and changes in ionic concentrations in live cells, multicellular preparations, or entire hearts. Here we review this technological progress demonstrating how each improvement in spatial or temporal resolution provided answers to old and provoked new questions. We further demonstrate how high-speed optical mapping of voltage and calcium can uncover pacemaking potential within the outflow tract myocardium, providing a developmental explanation of ectopic beats originating from this region in the clinical settings. (en)
Title	Studying dynamic events in the developing myocardium Studying dynamic events in the developing myocardium (en)
skos:prefLabel	Studying dynamic events in the developing myocardium Studying dynamic events in the developing myocardium (en)
skos:notation	RIV/00216208:11110/14:10281057!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(GA13-12412S), P(GAP302/11/1308), S
http://linked.open...iv/cisloPeriodika	2-3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Sedmera, David Šaňková, Barbora
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	48394
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/14:10281057
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Optical mapping; High-speed cameras; Heart; Embryo; Cardiac conduction system; Calcium imaging (en)
http://linked.open.../riv/klicoveSlovo	Embryo Calcium imaging Cardiac conduction system High-speed cameras Heart Optical mapping
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[12F44A8B4E21]
http://linked.open...i/riv/nazevZdroje	Progress in Biophysics and Molecular Biology
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Epigenetic factors in myocardial morphogenesis Development of mouse conduction system analyzed by 3D imaging and optical mapping
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	115
http://linked.open...iv/tvurceVysledku	Sedmera, David Šaňková, Barbora Vostárek, František
http://linked.open...ain/vavai/riv/wos	000344424700019
issn	0079-6107
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.pbiomolbio.2014.06.002
http://localhost/t...ganizacniJednotka	11110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software