About: Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:seeAlso
Description
  • PU.1 downregulation within hematopoietic stem and progenitor cells (HSPCs) is the primary mechanism for the development of acute myeloid leukemia (AML) in mice with homozygous deletion of the upstream regulatory element (URE) of PU.1 gene. p53 is a well-known tumor suppressor that is often mutated in human hematologic malignancies including AML and adds to their aggressiveness; however, its genetic deletion does not cause AML in mouse.
  • PU.1 downregulation within hematopoietic stem and progenitor cells (HSPCs) is the primary mechanism for the development of acute myeloid leukemia (AML) in mice with homozygous deletion of the upstream regulatory element (URE) of PU.1 gene. p53 is a well-known tumor suppressor that is often mutated in human hematologic malignancies including AML and adds to their aggressiveness; however, its genetic deletion does not cause AML in mouse. (en)
Title
  • Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice
  • Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice (en)
skos:prefLabel
  • Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice
  • Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice (en)
skos:notation
  • RIV/00216208:11110/14:10196519!RIV15-MSM-11110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(ED1.1.00/02.0109), P(GAP305/12/1033), P(GP13-12449P), P(GPP301/12/P380), S
http://linked.open...iv/cisloPeriodika
  • 39
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 1861
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/14:10196519
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • AML; p53; microRNA; differentiation; PU.1/p53; Aggressive acute myeloid leukemia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [8EE9E66CA0DE]
http://linked.open...i/riv/nazevZdroje
  • Oncogene
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 33
http://linked.open...iv/tvurceVysledku
  • Pospíšil, Vít
  • Savvulidi, Filipp Geirgievich
  • Stopka, Tomáš
  • Kužmová, Erika
  • Jonášová, Anna
  • Vargová, Karina
  • Bašová, Petra
  • Burda, Pavel
  • Staněk, Libor
  • Laslo, P.
  • Dluhošová, Martina
  • Steidl, U.
http://linked.open...ain/vavai/riv/wos
  • 000343239500004
issn
  • 0950-9232
number of pages
http://bibframe.org/vocab/doi
  • 10.1038/onc.2013.414
http://localhost/t...ganizacniJednotka
  • 11110
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software